Skip to main content
SpringerLink
Log in

Sequence of centromere separation of mitotic chromosomes in Chinese hamster

  • Published:
Chromosoma Aims and scope Submit manuscript

Abstract

Chromosome preparations in late metaphase cells from bone marrow of colcemid treated male Chinese hamsters were used to analyse the sequence of separation of sister centromeres. Chromatids of chromosomes 2 and 1 are the first ones to separate at centromeres, followed by members of group B, D and C. Some acrocentric chromosome is always the last one to separate at the centromere. The data point to a possible correlation between the position of a centromere in the separation sequence in the genome and the amount of centromeric heterochromatin as well as relation to the phenomenon of non-disjunction.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Aisenberg, E.J.: De l'effet de l'hypoet de l'hypertonie sur les mitoses. Bull. Histol. Techn. Micro. 123, 100–122 (1935)

    Google Scholar 

  • Arrighi, P.B., Saunders, P.O., Saunders, G.F., Hsu, T.C.: Distribution of repetitious DNA in human chromosomes. Experientia (Basel) 27, 964–966 (1971)

    Google Scholar 

  • Bregman, A.A.: Asynchronous centromere division in the Chinese hamster. Cytogenetics 11, 102–112 (1972)

    Google Scholar 

  • Carr, D.H.: Genetic basis of abortion. Ann. Rev. Genet. 5, 65–80 (1971)

    Google Scholar 

  • Hsu, T.C.: Longitudinal differentiation of chromosomes. Ann. Rev. Genet. 7, 153–176 (1973)

    Google Scholar 

  • Levan, A.: The effect of colchicine on root mitosis in Allium. Hereditas (Lund) 24, 471–486 (1938)

    Google Scholar 

  • Molè-Bajer, J.: Cinè-micrographic analysis of C-mitosis in endosperm. Chromosoma (Berl.) 9, 332–358 (1958)

    Google Scholar 

  • Taylor, J.H.: Asynchronous duplication of chromosomes in cultured cells of Chinese hamster. J. biophys. biochem. Cytol. 7, 455–464 (1960)

    Google Scholar 

  • Upcott, M.: The external mechanics of chromosomes VII: Abnormal mitosis in the pollengrain. Chromosoma (Berl.) 1, 178–190 (1939)

    Google Scholar 

  • Vig, B.K., Wodnicki, J.: Separation of sister centromeres in some chromosomes from cultured human leucocytes. J. Hered. 65, 149–152 (1974)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biology, University of Nevada, 89507, Reno, Nevada, USA

    Baldev K. Vig

  2. Institute of Zoology, Technische Hochschule, 6100, Darmstadt, Federal Republic of Germany

    Herbert G. Miltenburger

Authors
  1. Baldev K. Vig
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Herbert G. Miltenburger
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vig, B.K., Miltenburger, H.G. Sequence of centromere separation of mitotic chromosomes in Chinese hamster. Chromosoma 55, 75–80 (1976). https://doi.org/10.1007/BF00288329

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00288329

Keywords

Search

Navigation