Abstract
Using a special staining technique, a survey of the chromosomes of many mammalian species showed that constitutive heterochromatin is present in all cases and that the heterochromatin pattern appears to be specific and consistent or each chromosome and each taxon. Usually heavy heterochromatin is found in the centromeric areas, but terminal heterochromatin is not uncommon. Occasionally interstitial heterochromatin bands occur. In some species, such as the Syrian hamster and Peromyscus, many chromosome arms are completely heterochromatic.
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Arrighi, F. E., Hsu, T. C.: Localization of heterochromatin in human chromosomes. Cytogenetics 10, 81–86 (1971).
—: Saunders, P., Saunders, G. F.: Localization of repetitive DNA in the chromosomes of Microtus agrestis by means of in situ hybridization. Chromosoma (Berl.) 32, 224–236 (1970).
Bostock, C. J., Prescott, D. M.: Buoyant density of DNA synthesized at different stages of the S phase of mouse L cells. Exp. Cell Res. 64, 267–274 (1971).
Craig, A. P., Shaw, M. W.: Autoradiographic studies of the human Y chromosome. Chromosoma (Berl.) 32, 364–377 (1971).
Drets, M. E., Shaw, M. W.: Specific banding pattern of human chromosomes. Proc. nat. Acad. Sci. (Wash.) (in press).
Galton, M., Holt, S. F.: DNA replication patterns of the sex chromosomes in somatic cells of the Syrian hamster. Cytogenetics 3, 97–111 (1964).
Hsu, T. C.: Genetic cytology. In: Cells and tissues in culture, vol. 1 (E. N. Willmer, ed.), pp. 297–361. New York: Acad. Press Inc. 1965.
—, Baker, R. J., Utakoji, T.: The multiple sex chromosome system of American leaf-nosed bats (Chiroptera, Phyllostomidae). Cytogenetics 7, 27–38 (1968).
—, Benirschke, K.: An atlas of mammalian chromosomes, vol. 2. Berlin-Heidelberg-New York: Springer 1968.
—, Cooper, J. E. K., Mace, M. L., Brinkley, B. R.: Arrangement of centromeres in mouse cells. Chromosoma (Berl.) 34, 73–87 (1971).
—, Somers, C. E.: Effect of 5-bromodeoxyuridine on mammalian chromosomes. Proc. nat. Acad. Sci. (Wash.) 47, 396–403 (1961).
Kreizinger, J. D., Shaw, M. W.: Chromosomes of Peromyscus (Bodentia, Cricetidae). II. The Y chromosome of Peromyscus maniculatus. Cytogenetics 9, 52–70 (1970).
Ohno, S., Beçak, W., Beçak, M. L.: X-autosome ratio and the behavior pattern of individual X-chromosomes in placental mammals. Chromosoma (Berl.) 15, 14–30 (1964).
Pardue, M. L., Gall, J. G.: Chromosomal localization of mouse satellite DNA. Science 170, 1356–1358 (1970).
Wurster, D. H., Benirschke, K.: Indian muntjac, Muntiacus muntjak: A deer with a low diploid chromosome number. Science 168, 1364–1366 (1970).
Yasmineh, W. G., Yunis, J. J.: Localization of mouse satellite DNA in constitutive heterochromatin. Exp. Cell Res. 59, 69–75 (1970).
— Satellite DNA in calf heterochromatin. Exp. Cell Res. 64, 41–48 (1971).
Yunis, J. J., Yashmineh, W. G.: Satellite DNA in constitutive heterochromatin of the guinea pig. Science 168, 263–265 (1970).
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Supported in part by Research Grant GB-13661 from the National Science Foundation.
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Hsu, T.C., Arrighi, F.E. Distribution of constitutive heterochromatin in mammalian chromosomes. Chromosoma 34, 243–253 (1971). https://doi.org/10.1007/BF00286150
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DOI: https://doi.org/10.1007/BF00286150