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Application of the differential reactivity to human X-chromosomes

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Abstract

In the present investigation the identification of human X-chromosomes among the C group was studied by means of differential reactivity induced by low temperature. The chromosome No. 6′ in the male exhibited the specific segmentai patterns which were strikingly similar to those of the female. The segmental patterns of the two chromosomes of No. 6′ in the female were identical in the comparative study. Autoradiographic studies using 3H-thymidine labelling also showed that one of the two chromosomes of No. 6′ in the female was replicated later than the remainders. From this point of view, the chromosome No. 6′ with the specific segmental patterns can be recognized as the X-chromosome. It is concluded that this technique may be valuable for the absolute identification of the human X-chromosomes.

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Authors and Affiliations

  1. Department of Anatomy, School of Medicine, Kanazawa University, Japan

    Yukimasa Shiraishi

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  1. Yukimasa Shiraishi
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Shiraishi, Y. Application of the differential reactivity to human X-chromosomes. Chromosoma 34, 88–93 (1971). https://doi.org/10.1007/BF00285518

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  • DOI: https://doi.org/10.1007/BF00285518

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