Summary
In a series of 1000 prenatal diagnoses, four cases were found with chromsome changes. The probable in vitro origin of these changes was demonstrated by starting several parallel cultures simultaneously and by repeating the amniocenteses and chromosome analyses.
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Wahlström, J. Four cases of chromosome changes detected in course of prenatal diagnosis and probably originating in vitro. Hum Genet 41, 265–268 (1978). https://doi.org/10.1007/BF00284760
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DOI: https://doi.org/10.1007/BF00284760