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Methodisch einfache Cytodiagnostik carcinogen-induzierter Lungen-Tumoren am syrischen Goldhamster

A simple method for the cytodiagnosis of carcinogenically induced lung tumors in the Syrian golden hamster

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Summary

After inducing lung tumors with N-Methyl-N-Nitrosourea (intratracheally) and Dibutylnitrosamine (subcutaneously) in the Syrian golden hamster, a simple method was devised for collecting bronchial secretions. The results of the cytological and histological investigation are described.

Zusammenfassung

Am syrischen Goldhamster wird nach Induktion von Lungentumoren mit N-Methyl-N-Nitrosoharnstoff (intratracheal) und Dibutylnitrosamin (subcutan) eine einfache Methodik zur Gewinnung von Bronchialsekret und die Ergebnisse der cytologischen und histologischen Untersuchung beschrieben.

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Literatur

  • Althoff,J., Krüger,F.W., Mohr,U., Schmähl,D.: Dibutylnitrosamine carcinogenesis in Syrian Golden and Chinese Hamsters. Proc. Soc. exp. Biol. Med. 136, 168–173 (1971).

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  • Herrold,K.M.: Upper respiratory tract tumors induced in Syrian Hamsters by N-methyl- N-nitrosourea. Int. J. Cancer 6, 217–222 (1970).

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  • Saffiotti,U., Cefis,F., Kolb,L.H.: A method for the experimental induction of bronchogenic carcinoma. Cancer Ees. 28, 104–124 (1968).

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Authors and Affiliations

  1. Abteilung für experimentelle Pathologie und Pathologisches Institut der Medizinischen Hochschule Hannover, Bundesrepublik Deutschland

    J. Hilfrich, J. Bauer, Z. Atay & U. Mohr

Authors
  1. J. Hilfrich
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  2. J. Bauer
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  3. Z. Atay
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  4. U. Mohr
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Hilfrich, J., Bauer, J., Atay, Z. et al. Methodisch einfache Cytodiagnostik carcinogen-induzierter Lungen-Tumoren am syrischen Goldhamster. Z. Krebsforsch. 79, 71–74 (1973). https://doi.org/10.1007/BF00284341

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  • DOI: https://doi.org/10.1007/BF00284341

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