Abstract
The distribution of gaps, breaks, exchanges and other effects induced by Mitomycin C on human chromosomes was analysed to examine the possibility of a correlation between chromosome lesions and regions of repetitive DNA. Homologous and non-homologous exchanges between chromosomes Nos. 1, 9 and 16, and also between and with the acrocentric chromosomes were more frequent than expected, but breaks and gaps appeared to be located randomly with regard to chromosome light and dark bands.
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Bourgeois, C.A. Distribution of Mitomycin C-induced damage in human chromosomes with special reference to regions of repetitive DNA. Chromosoma 48, 203–211 (1974). https://doi.org/10.1007/BF00283964
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DOI: https://doi.org/10.1007/BF00283964