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The relationship between repetitive DNA and chromosomal bands in man

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Abstract

The relationship between chromosomal bands and repetitious DNA has been investigated by means of the quinacrine fluorescence technique and in situ hybridization with c-RNA to different fractions of repetitive DNA. A comparison of the Q bands with the labelling patterns obtained showed a preferential distribution of repetitive DNA's at Cot's ranging from 0 to 5 in those regions that are Q band positive. A distinct labelling was also observed in the pericentromeric regions and in some telomeres. It is suggested that the distribution of repetitive DNA along the chromosomes plays an important role in band formation.

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  1. Medical Genetics Division, Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis

    Otto Sanchez & Jorge J. Yunis

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  1. Otto Sanchez
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  2. Jorge J. Yunis
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Sanchez, O., Yunis, J.J. The relationship between repetitive DNA and chromosomal bands in man. Chromosoma 48, 191–202 (1974). https://doi.org/10.1007/BF00283963

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  • DOI: https://doi.org/10.1007/BF00283963

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