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Implications of somatic recombination and sister chromatid exchange in Bloom's syndrome and cells treated with mitomycin C

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Summary

It is suggested that the somatic recombination observed in Bloom's syndrome and cells treated with mitomycin C may be the result of selection for recombination events that can occur only between homologous segments of DNA, rather than a result of somatic pairing in the nucleus.

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Authors and Affiliations

  1. Department of Medical Genetics, City of Hope National Medical Center, Duarte, California, USA

    David E. Comings

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  1. David E. Comings
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Supported by N.I.H. Grant GM-15886.

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Comings, D.E. Implications of somatic recombination and sister chromatid exchange in Bloom's syndrome and cells treated with mitomycin C. Hum Genet 28, 191–196 (1975). https://doi.org/10.1007/BF00278544

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  • DOI: https://doi.org/10.1007/BF00278544

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