Skip to main content
Log in

Parameter estimation techniques for transport equations with application to population dispersal and tissue bulk flow models

  • Published:
Journal of Mathematical Biology Aims and scope Submit manuscript

Abstract

We develop techniques for estimating the coefficients, boundary data, and initial data associated with transport equations (or more generally, parabolic distributed models). Our estimation schemes are based on cubic spline approximations, for which convergence results are given. We discuss the performance of these techniques in two investigations of biological interest: (1) transport of labeled sucrose in brain tissue white matter, (2) insect dispersal that cannot be modeled by a random diffusion mechanism alone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Balakrishnan, A. V.: Applied functional analysis. Berlin-Heidelberg-New York: Springer 1976

    Google Scholar 

  2. Banks, H. T.: A survey of some problems and recent results for parameter estimation and optimal control in delay and distributed parameter systems. Proc. Conf. on Volterra and Functional Differential Equations, (VPISU, Blacksburg, June 10–13, 1981), (LCDS Tech. Rep. 81-19, July, 1981, Brown Univ.) pp. 3–24. New York: Marcel Dekker 1982

    Google Scholar 

  3. Banks, H. T., Crowley, J. M.: Parameter estimation for distributed systems arising in elasticity. Proc. Symposium on Engineering Sciences and Mechanics (National Cheng Kung University, Tainan, Taiwan, Dec. 28–31, 1981). LCDS Tech. Rep. 81-24, November, 1981, Brown Univ.

  4. Banks, H. T., Crowley, J. M.: Parameter estimation in Timoshenko beam models, LCDS # 82-14, Brown Univ., June, 1982; J. Astronautical Sci., to appear

  5. Banks, H. T., Crowley, J. M., Kunisch, K.: Cubic spline approximation techniques for parameter estimation in distributed systems. LCDS Tech. Rep. 81-25, Nov., 1981, Brown Univ.; IEEE Trans. Auto. Control, to appear

  6. Banks, H. T., Daniel, P. L.: Parameter estimation of nonlinear nonautonomous distributed systems, Proc. 20th IEEE Conf. on Decision and Control, San Diego, Dec., 1981, pp. 228–232

  7. Banks, H. T., Daniel, P. L.: Estimation of variable coefficients in parabolic distributed systems, LCDS Tech. Rep. 82-22, Sept. 1982, Brown Univ.; IEEE Trans. Auto. Control, submitted

  8. Banks, H. T., Kunisch, K.: An approximation theory for nonlinear partial differential equations with applications to identification and control, LCDS Tech. Report 81-7, Brown Univ., April, 1981; SIAM J. Control and Optimization 20, 815–849 (1982)

  9. Daniel, P. L.: Spline-based approximation methods for the identification and control of nonlinear functional differential equations. Ph.D. Thesis, Brown Univ., Providence, RI, June 1981

    Google Scholar 

  10. Dobzhansky, T., Powell, J. R., Taylor, C. E., Andrezy, M.: Ecological variables affecting the dispersal behavior of Drosophila pseudoobscura and its relatives. American Naturalist 114, 325–334 (1979)

    Google Scholar 

  11. Kareiva, P.: Experimental and mathematical analyses of herbivore movement: Quantifying the influence of plant spacing and quality of foraging discrimination. Ecological Monographs 52, 261–282 (1982)

    Google Scholar 

  12. Kyner, W. T., Rosenberg, G. A.: Parameter estimation techniques used in the determination of the bulk flow of brain interstitial fluid. In: Hoppenstead, F. (ed) Mathematical aspects of physiology vol. 19, pp. 385–388. Lec. in Applied Math., Amer. Math. Soc. 1981

  13. Levin, S.: The role of theoretical ecology in the description and understanding of populations in heterogeneous environments. American Zoologist 21, 865–875 (1981)

    Google Scholar 

  14. Okubo, A.: Diffusion and ecological problems: Mathematical models. Biomathematics, Vol. 10. Berlin-Heidelberg-New York: Springer 1980

    Google Scholar 

  15. Pazy, A.: Semigroups of linear operators and applications to partial differential equations. Lecture Notes No. 10, University of Maryland, 1974

  16. Prenter, P. M.: Splines and variational methods. New York: Wiley-Interscience 1975

    Google Scholar 

  17. Rosenberg, G. A., Kyner, W. T.: Gray and white matter brain-blood transfer constants by steadystate tissue clearance in cat. Brain Res. 193, 59–66 (1980)

    Google Scholar 

  18. Rosenberg, G. A., Kyner, W. T., Estrada, E.: Bulk flow of brain interstitial fluid under normal and hyperosmolar conditions. Am. J. Physiol. 238 (Renal Fluid Electrolyte Physiol. 7) F42-F49 (1980)

    Google Scholar 

  19. Rudin, W.: Functional analysis. New York: McGraw-Hill 1973

    Google Scholar 

  20. Sives, C., Sato, L.: Computer estimation of parameters in a brain bluid transport equation: A cubic spline approximation method. LCDS Report # M-82-6, Brown University, May, 1982

  21. Skellam, J. G.: Random dispersal in theoretical populations. Biometrika, 38, 196–218 (1951)

    Google Scholar 

  22. Sokal, R. R., Rohlf, F. J.: Biometry. San Francisco: W. H. Freeman 1981

    Google Scholar 

  23. Southwood, T. R. E.: Ecological methods. London: Halstead Press 1978

    Google Scholar 

  24. Taylor, R. A. J.: The behavioral basis of redistribution I. The Δ-model concept. Journal of Animal Ecology 50, 573–586 (1981)

    Google Scholar 

  25. Taylor, R. A. J.: A family of regression equations describing the density distribution of dispersing organisms. Nature 286, 53–55 (1980)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

This research has been supported in part by the Air Force Office of Scientific Research under contract # AF-AFOSR # 81-0198, in part by the National Science Foundation under contract # MCS 79-05774-05, and in part by the U.S. Army Research Office under contract # ARO-DAAG-29-79-C-0161

Collection of data concerning beetle dispersal was supported by NSF grant DEB 77-25120 to Richard B. Root. Subsequent computer analyses of these dispersal data were supported in part by NSF grant DEB 8207117 to P. Kareiva

Rights and permissions

Reprints and permissions

About this article

Cite this article

Banks, H.T., Kareiva, P. Parameter estimation techniques for transport equations with application to population dispersal and tissue bulk flow models. J. Math. Biology 17, 253–273 (1983). https://doi.org/10.1007/BF00276516

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00276516

Key words

Navigation