Summary
Temperature-sensitive mutants affecting maltose utilization in the yeast Saccharomyces cerevisiae have been isolated. Two such mutants although failing to ferment maltose at the restrictive temperature, have normal induced level of maltase. The third mutant (UNT-37) not only failed to ferment maltose but has 5–6 fold less induced level of maltase at the restrictive temperature than the parental strain The genetic control mechanisms of maltase induction and maltose utilization have been discussed.
Similar content being viewed by others
References
Berge A. M. A. ten, Zoutewelle, G., van de Poll, K. W.: Regulation of maltose fermentation in Saccharomyces carlsbergensis. I. The function of the gene MAL6, as recognized by mal-6-mutants. Molec. gen. Genet. 123, 233–246 (1973)
Khan, N. A.: Constitutive alpha-methylglucosidase synthesis in yeast. Molec. gen. Genet. 133, 363–365 (1974)
Khan, N. A., Eaton, N. R.: Genetic control of maltase formation in yeast. I. Strains producing high and low basal levels of enzyme. Molec. gen. Genet. 112, 317–322 (1971)
Khan, N. A., Zimmermann, F. K., Eaton, N. R.: Genetic control of maltase formation in yeast. II. Evidence for a gene regulating the level of maltase production. Molec. gen. Genet. 124, 365–367 (1973)
Zamenhoff, D.: In: Colowick, S. P., Kaplan, N. O., Methods in enzymology, vol. 3. New York: Academic Press 1958
Zimmermann, F. K., Khan N. A., Eaton, N. R.: Identification of new genes involved in disaccharide fermentation in yeast. Molec. gen. Genet. 123, 29–41 (1973)
Author information
Authors and Affiliations
Additional information
Communicated by F. Kaudewitz
Rights and permissions
About this article
Cite this article
Khan, N.A. Genetic control of maltase formation in yeast. Molec. Gen. Genet. 136, 55–61 (1975). https://doi.org/10.1007/BF00275448
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00275448