Skip to main content
SpringerLink
Log in

Regional mapping of human chromosome 3. Assignment of a glutathione peroxidase-1 gene to 3p13→3q12

  • Original Investigations
  • Published:
Human Genetics Aims and scope Submit manuscript

Summary

The segregation of human glutathione peroxidase-1 (GPX1, EC 1.11.1.9) was followed in a series of human-mouse somatic cell hybrids carrying various fragments of human chromosome 3. These fragments originated from translocations in the parental human fibroblasts or from spontaneous deletions which occurred during the cultivation of hybrid clones. The smallest region of overlap found for the position of GPX 1 was 3p13→3q12.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Beutler E, West C, Beutler B (1974) Electrophoretic polymorphism of glutathione peroxidase. Ann Hum Genet 38:163–169

    Article  CAS  Google Scholar 

  • Flohé L, Eisele B, Wendel A (1971) Glutathion-Peroxidase, I. Hoppe Seylers Z Physiol Chem 352:151–158

    Article  Google Scholar 

  • Fidzianska E, Abramowicz T, Pawlowska B, Glogowska J, Zaremba J, Wijnen LMM, Meera Khan P (1979) Regional localization of GPX-1 on human chromosome 3. Vth International Workshop on Human Gene Mapping. Edinburgh (abstract)

  • Grzeschik K-H (1973) Syrian hamster-human somatic cell hybrids. Isolation and characterization. Humangenetik 20: 211–218

    Article  CAS  Google Scholar 

  • Grezeschik K-H (1980) Assignment of a structural gene for a fourth human diaphorase (DIA4) to chromosome 16 in manmouse somatic cell hybrids. Hum Genet 53:189–193

    Google Scholar 

  • Wijnen LMM, Monteba-Van Heuvel M, Pearson PL, Meera Khan P (1978) Assignment of a gene for glutathione peroxidase (GPX1) to human chromosome 3. Cytogenet Cell Genet 22:232–235

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Humangenetik der Universität Münster, Vesaliusweg 12-14, D-4400, Münster, Germany

    Renate Johannsmann, B. Hellkuhl & K. -H. Grzeschik

Authors
  1. Renate Johannsmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. Hellkuhl
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. -H. Grzeschik
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Johannsmann, R., Hellkuhl, B. & Grzeschik, K.H. Regional mapping of human chromosome 3. Assignment of a glutathione peroxidase-1 gene to 3p13→3q12. Hum Genet 56, 361–363 (1981). https://doi.org/10.1007/BF00274693

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00274693

Keywords

Search

Navigation