Summary
The reaction of wounds to Epigard was studied in rats. Epigard adhered firmly to wounds and was infiltrated towards the 9th day by a granulation tissue rich in cells. Foreign body reaction was marked on the 14th day. Changing the Epigard repeatedly showed a faster ingrowth of tissue which was highly vascularized. Vascularization of the wound bed was more pronounced under Epigard treatment than with the use of homograft skin. Temporary covering of a fresh surgical wound with Epigard was as effective as with homograft skin in keeping the wound ready for autotransplantation.
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Šmahel, J., Zellweger, G. Reaction of a wound to Epigard® in animal experiments. Chir Plastica 3, 219–226 (1976). https://doi.org/10.1007/BF00274298
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DOI: https://doi.org/10.1007/BF00274298