Summary
Trisomy 9p with de novo 9/15 translocation and 9p isochromosome was observed in a mentally defective boy with typical clinical features for this syndrome. This chromosomal aberration is probably caused by the pericentric inversion of chromosome 9 of the patient's father.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Edwards, J. H., Fraccaro, M., Davies, P., Young, R. B.: Structural heterozygosis in man: Analysis of two families. Ann. Hum. Genet. 26, 163–178 (1962)
Ghymers, D., Hermann, B., Disteche, C., Frederic, J.: Tétrasomie partielle du chromosome 9, à l'état de mosaique, chez un enfant porteur de malformations multiples. Hum. Genet. 20, 273–282 (1973)
Hansmann, J.: Structural variability of human chromosome 9 in relation to its evolution. Hum. Genet. 31, 247–262 (1976)
Hoehn, H., Engle, W., Reinwein, H.: Presumed trisomy for the short arm of chromosome No. 9 not due to inherited translocation. Hum. Genet. 12, 175–181 (1971)
Howard, P. N., Stoddard, G. R.: Pericentric inversions of chromosome 9: Benign or harmful? V. International Congress of Human Genetics, Mexico, Amsterdam: Exc. Med. 1976
Käosaar, M. E., Mikelsaar, A.-V. N., Talvik, T. A., Mikelsaar, R. V.-A.: A case of trisomy for the short arm of chromosome No. 9 (+9(p)). Hum. Genet. 34, 77–80 (1976)
Lejeune, J., Berger, R., Rethoré, M.-O., Salmon, C., Kaplan, M.: Translocation C∼F familiale determinant une trisomie pour le bras court du chromosome 12. Ann. Génét. 9, 12–18 (1966)
Lurie, I. W., Lazjuk, G. I., Gurevich, D. B., Usoev, S. S.: Genetics of the +p9 syndrome. Hum. Genet. 32, 23–33 (1976)
Mastrojacovo, P., Dallapiccola, B., Gugliantini, F., Segni, G.: itTrisomia 9p da translocatione paterna t(6;9)(q27p13). Riv. Ital. Ped. 2, 115–123 (1976)
Orye, E., Verhaaren, H., Egmond, H. van, Devloo-Blancquaert, A.: A new case of the trisomy 9p syndrome. Clin. Genet. 7, 134–143 (1975)
Rethoré, M.-O., Hoehn, H., Rott, H.-D., Couturier, J., Dutrillaux, B., Lejeune, J.: Analyse de la trisomie 9p par dénaturation menagée. A propos d'un nouveau cas. Hum. Genet. 18, 129–138 (1973)
Rutten, F. J., Scheres, J. M. J. C., Hustinx, T. W. J., Haar, B. G. A. ter: A presumptive tetrasomy for the short arm of chromosome 9. Hum. Genet. 25, 163–170 (1974)
Schinzel, A.: Autosomal chromosome aberration. Ergebn. Inn. Med. Kinderheilk. N.F. 38. Berlin, Heidelberg, New York: Springer 1976
Smith, C., McCaa, A., Kelly, T. E.: Trisomy 9p with an isochromosome of 9p. Hum. Genet. 42, 93–97 (1978)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sandig, K.R., Mücke, J. & Veit, H. Trisomy 9p resulting from de novo 9/15 translocation and a 9p isochromosome. Hum Genet 52, 175–178 (1979). https://doi.org/10.1007/BF00271570
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00271570