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Genetic analysis of antisuppressor mutants in the fission yeast Schizosaccharomyces pombe

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Summary

Fourteen unlinked sin genes could be mutated to recessive antisuppressor alleles preventing the expression of suppressors in the fission yeast Schizosaccharomyces pombe. cyh1 alleles, resistant to the ribosomal inhibitor cycloheximide, also have some antisuppressor effect. The genetical and physiological characterization of these mutants is consistent with the hypothesis that they affect components of the messenger RNA translation machinery such as tRNA modifying enzymes or ribosomal proteins.

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Authors and Affiliations

  1. Institute of General Microbiology, University of Bern, Switzerland

    P. Thuriaux, M. Minet, F. Hofer & U. Leupold

  2. Eidgenössische Forschungsanstalt für Milchwirtschaft, Liebefeld-Bern, Switzerland

    F. Hofer

Authors
  1. P. Thuriaux
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  2. M. Minet
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  3. F. Hofer
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  4. U. Leupold
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Communicated by F. Kaudewitz

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Thuriaux, P., Minet, M., Hofer, F. et al. Genetic analysis of antisuppressor mutants in the fission yeast Schizosaccharomyces pombe . Molec. Gen. Genet. 142, 251–261 (1975). https://doi.org/10.1007/BF00271250

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  • DOI: https://doi.org/10.1007/BF00271250

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