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Specificity of polarity suppression in E. coli: Correction of defects in gene N, but not in gene Q, of phage λ

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Summary

The bacterial mutation psuA1, known as (suA) a polarity suppressor, partially relieves all N defects in bacteriophage lambda growth. No evidence is found that psuA1 relieves Q defects in lambda growth. Specific mechanisms of action by the N and Q gene products are discussed.

The psuA1 mutation was also found to suppress IS1 type but not IS2 type insertion mutations in lambda.

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Authors and Affiliations

  1. Laboratoire de Génétique, Université libre de Buxelles, Rhode St Genèse, (Belgium)

    C. Dambly

  2. Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland

    D. Court

  3. Départment de Biologie Moléculaire, Institut Pasteur, Paris, (France)

    P. Brachet

Authors
  1. C. Dambly
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  2. D. Court
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  3. P. Brachet
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Communicated by G. Bertani

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Dambly, C., Court, D. & Brachet, P. Specificity of polarity suppression in E. coli: Correction of defects in gene N, but not in gene Q, of phage λ. Molec. Gen. Genet. 148, 175–182 (1976). https://doi.org/10.1007/BF00268383

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  • DOI: https://doi.org/10.1007/BF00268383

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