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Body-weight and chromosome aberrations induced by X-rays in somatic cells of Drosophila melanogaster

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Summary

Body-weight has been shown to influence the final expression of genetic damage by X-rays in Drosophila melanogaster. If larvae of Drosophila were raised up to the third instar in media containing different amounts of the same nutrient and in different conditions of crowding a positive correlation was observed between body-weight and frequency of chromosome aberrations induced by a given dose of X-rays in the somatic cells of their nerve ganglia. This effect, present in both sexes, is most plausibly attributed to a different capacity of big and small larvae for repairing radiation damage.

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References

  • Auerbach, Ch., Moser, H.: An analysis of the mutagenic action of formaldehyde food. Io Sensitivity of Drosophila germ cells. Z. indukt. Abstamm.-u. Vererbungsl. 85, 479–504 (1953)

    Google Scholar 

  • Bajerska, A., Liniecki, J.: The influence of temperature at irradiaton in vitro on the yield of chromosomal aberrations in peripheral blood lymphocytes. Int. J. Radiat. Biol. 16, 213–232 (1953)

    Google Scholar 

  • Clark, A.M.: Influence of the nutritional state of females on the frequency of X/O males recovered after matings with irradiated males. DIS 49, 75 (1972)

    Google Scholar 

  • Conger, A.D.: The effect of oxygen on the radiosensitivity of mammalian cells. Radiology 66, 63–69 (1956)

    Google Scholar 

  • De Marco, A.: Body-weight and crossing-over in Drosophila melanogaster. Atti AGI 1976 (in press)

  • Evans, H.J.: Repair and recovery from chromosome damage after fractionated X-rays dosage. In: Genetical aspects of radiosensitivity: Mechanism of repair, pp. 31–48. Vienna: Inter. Atomic Energy Agency 1966

    Google Scholar 

  • Evans, H.J.: Repair and recovery from chromosome damage induced by fractionated X-ray exposures. In: Radiation research, pp. 482–501. Amsterdam: North Holland Publ. Comp. 1967

    Google Scholar 

  • Gatti, M., Pimpinelli, S., De Marco, A., Tanzarella, C.: Chemical induction of chromosome aberrations in somatic cells of Drosophila melanogaster. Mutation Res. 33, 201–212 (1975)

    Google Scholar 

  • Gatti, M., Tanzarella, C., Olivieri, G.: Analysis of the chromosome aberrations induced by X-rays in somatic cells of Drosophila melanogaster. Genetics 77, 701–719 (1974)

    Google Scholar 

  • Herskowitz, I.H.: An influence of maternal nutrition upon the gross chromosomal mutation frequency recovered from X-rayed sperm of Drosophila melanogaster. Genetics 48, 703–710 (1963)

    Google Scholar 

  • Proust, J.P., Sankaranarayanan, K., Sobels, F.: The effect of treating Drosophila females with actynomycin-D on the yields of dominant lethals, translocations and recessive lethals recovered from X-irradiated spermatozoa. Mutation Res. 16, 65–76 (1972)

    Google Scholar 

  • Revell, S.H.: Chromosome breakage by X-rays and radiomimetic substances in Vicia. Heredity (Suppl.) 6, 107–124 (1953)

    Google Scholar 

  • Sax, K., Enzman, B.V.: The effect of temperature of X-ray induced chromosome aberrations. Proc. nat. Acad. Sci. (Whas.) 25, 397–405 (1939)

    Google Scholar 

  • Thoday, J.M., Read, J.: Effect of oxygen on the frequency of chromosome aberrations produced by X-rays. Nature (Lond.) 160, 608 (1947)

    Google Scholar 

  • Watson, G.E., Gillies, N.E.: The oxygen enhancement ratio for X-ray induced chromosomal aberrations in cultured human lymphocytes. Int. J. Radiat. Biol. 17, 279–283 (1970)

    Google Scholar 

  • Whitehouse, H.L.K.: Towards an understanding of the mechanism of heredity. London: Edward Arnold 1965

    Google Scholar 

  • Zeiger, E.: Dietary effects on the mutagenicity of N-nitroso compounds in the host-mediated assay. Abstr. Ist. Int. Conf. on Environm. Mutagens, Asilomar 15 (1973)

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Communicated by Ch. Auerbach

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De Marco, A., Belloni, M.P. Body-weight and chromosome aberrations induced by X-rays in somatic cells of Drosophila melanogaster . Molec. Gen. Genet. 146, 1–4 (1976). https://doi.org/10.1007/BF00267976

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  • DOI: https://doi.org/10.1007/BF00267976

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