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Ribosomal mutations affect non-specifically the stability of sex factors in Escherichia coli

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The effect of ribosomal mutations on the stability of episomes was tested by isolating ribosomal and non-ribosomal mutations in strains carrying episomes. The stability was tested at 30°C and 40°C. Since episomes in general are less stable (get lost) at higher temperatures, and various types of mutations, ribosomal and non-ribosomal, decreased the stability of episomes, we suggest that event(s) which lead to episome instability at higher temperatures, can happen in strains carrying various mutations including ribosomal mutations, at lower temperatures.

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Communicated by H. G. Wittmann

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Eskind, S., Apirion, D. Ribosomal mutations affect non-specifically the stability of sex factors in Escherichia coli . Molec. Gen. Genet. 133, 209–212 (1974). https://doi.org/10.1007/BF00267670

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  • DOI: https://doi.org/10.1007/BF00267670

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