Summary
The effect of ribosomal mutations on the stability of episomes was tested by isolating ribosomal and non-ribosomal mutations in strains carrying episomes. The stability was tested at 30°C and 40°C. Since episomes in general are less stable (get lost) at higher temperatures, and various types of mutations, ribosomal and non-ribosomal, decreased the stability of episomes, we suggest that event(s) which lead to episome instability at higher temperatures, can happen in strains carrying various mutations including ribosomal mutations, at lower temperatures.
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References
Apirion, D.: Altered ribosomes in a suppressor strain of Escherichia coli. J. molec. Biol. 16, 28–301 (1966)
Ohlsson, B.M., Strigini, P.F., Beckwith, J.R.: Allelic amber and ochre suppressors. J. molec. Biol. 36, 209–218 (1968)
Stadler, J., Adelberg E.A.: Temperature dependence of sex-factor maintenance in Escherichia coli K-12. J. Bact. 109, 447–449 (1972)
Yamagata, H., Uchida, H.: Chromosomal mutations affecting the stability of sex-factors in Escherichia coli. J. molec. Biol. 63, 281–294 (1972)
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Communicated by H. G. Wittmann
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Eskind, S., Apirion, D. Ribosomal mutations affect non-specifically the stability of sex factors in Escherichia coli . Molec. Gen. Genet. 133, 209–212 (1974). https://doi.org/10.1007/BF00267670
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DOI: https://doi.org/10.1007/BF00267670