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Mapping of the locus involved in the catabolic oxidation of D-amino acids in Pseudomonas aeruginosa PAO

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Summary

Mutants of Pseudomonas aeruginosa PAO deficient in their utilization of DL-valine have been found to have lost their capacity to utilize DL-alanine and L-proline. Use of conjugal and transductional mediated gene transfers have established the chromosomal location of this gene and also its pleotropic function in the induction of the D-amino acid oxidase, involved in the oxidative utilization of DL-valine, DL-alanine and L-proline. These point mutations are clustered in a single locus designated as Val D and mapped around the 19th minute on the chromosome.

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Communicated by W. Gajewski

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Manoharan, T.H., Jayaraman, K. Mapping of the locus involved in the catabolic oxidation of D-amino acids in Pseudomonas aeruginosa PAO. Molec. Gen. Genet. 164, 51–56 (1978). https://doi.org/10.1007/BF00267598

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