Summary
A fine-structure analysis of the white locus in Drosophila hydei was carried out by means of allele recombination. Four mutants, derived from wild type, mapped at three subloci. These are possibly homologous to the main subloci 2, 3, and 4 of D. melanogaster. Three secondary mutants, derived from the primary w iv allele, were located in the proximal part of the gene. One of them appeared as a homoallele of the original w iv, whereas the remaining two are better explained either as double mutants or as mutants which facilitate irregular exchange.
Intragenic recombination at the white locus seems to be more frequent in D. hydei than in D. melanogaster. The comparatively high incidence is probably a general characteristic, common to intragenic and intergenic recombination in D. hydei.
Similar content being viewed by others
References
Breugel, F. M. A. van: An analysis of white-mottled mutants in Drosophila hydei, with observations on X-Y exchanges in the male. Genetica 41, 589–625 (1970)
Breugel, F. M. A. van, Ray, A., Gloor, H.: A comparison of banding patterns in salivary gland chromosomes of two species of Drosophila. Genetica 39, 165–192 (1968)
Carlson, E. A.: Comparative genetics of complex loci. Quart. Rev. Biol. 34, 33–67 (1959)
Carlson, P. S.: A genetic analysis of the rudimentary locus of Drosophila melanogaster. Genet. Res. (Camb.) 17, 53–81 (1971)
Chovnick, A., Ballantyne, G. H., Holm, D. G.: Studies on gene conversion and its relationship to linked exchange in Drosophila melanogaster. Genetics 69, 179–209 (1971)
Clausen, R. E.: Inheritance in Drosophila hydei. I. white and vermilion eye colors. Amer. Natur. 57, 52–58 (1923)
Finnerty, V. G., Duck, P., Chovnick, A.: Studies on genetic organization in higher organisms. II. Complementation and fine structure of the maroon-like locus of Drosophila melanogaster. Proc. nat. Acad. Sci. (Wash.) 65, 939–946 (1970)
Frei, H.: New white alleles by recombination in Drosophila hydei. Drosophila Information Service 50, 165–166 (1973)
Frei, H.: Unterschiedliche Strahlenempfindlichkeit in der Spermatogenese von Drosophila hydei, Letalraten und die Bedeutung der arteigenen genetischen Organisation. Archiv für Genetik 47, 136–171 (1974)
Green, M. M.: Spatial and functional properties of pseudo-alleles at the white locus in Drosophila melanogaster. Heredity 13, 303–315 (1959a)
Green, M. M.: Putative non-reciprocal crossing over in Drosophila melanogaster. Z. Vererbungsl. 90, 375–384 (1959b)
Green M. M.: Non-homologous pairing and crossing over in Drosophila melanogaster. Genetics 44, 1243–1256 (1959c)
Green, M. M.: Double crossing over or gene conversion at the white loci in Drosophila melanogaster?. Genetics 45, 15–18 (1960)
Green, M. M.: Unequal crossing over and the genetical organization of the white locus of Drosophila melanogaster. Z. Vererbungsl. 94, 200–214 (1963)
Green, M. M.: Genetic fine structure in Drosophila. In: Genetics today (Proc. XIth Int. Congr. Genet., The Hague 1963; Geerts, S. J., ed.) vol. 2, p. 37–49. Oxford: Pergamon Press 1965
Green, M. M.: Polarized pairing and recombination in tandem duplications of the white gene in Drosophila melanogaster. Genetics 54, 881–885 (1966)
Green, M. M.: Controlling element mediated transpositions of the white gene in Drosophila melanogaster. Genetics 61, 429–441 (1969)
Gregg, T. G.: The production of attached-X chromosomes in Drosophila hydei. Univ. Texas Publ. 5721, 238–245 (1957)
Judd, B. H.: Studies on some position pseudo-alleles at the white region in Drosophila melanogaster. Genetics 44, 34–42 (1959)
Judd, B. H.: The structure of intralocus duplication and deficiency chromosomes produced by recombination in Drosophila melanogaster, with evidence for polarized pairing. Genetics 49, 253–265 (1964)
Kalisch, W.-E., Rasmuson, B.: Changes of zeste phenotype induced by autosomal mutations in Drosophila melanogaster. Hereditas (Lund) 78, 97–104 (1974)
Kobel, H. R., Gloor, H.: Drosophila species: new mutants, D. hydei. Report of H. Gloor. Drosophila Information Service 47, 47–52 (1971)
Lindsley, D. L., Grell, E. H.: Genetic variations of Drosophila melanogaster. Carnegie Inst. Wash. Publ. 627 (1968)
Spencer, W. P.: Gene homologies and the mutants of Drosophila hydie. In: Genetics, paleontology, and evolution (Jepsen, G. L., Mayr, E., Simpson, G. G., eds.) p. 23–44. Princeton N.J.: Princeton University Press 1949
Spencer, W. P.: Genetic studies on Drosophila mulleri. II. Linkage maps of the X and chromosome II with special reference to gene and chromosome homologies. Univ. Texas Publ. 5721, 206–217 (1957)
Wasserman, M.: Cytological studies of the repleta group. Univ. Texas Publ. 5422, 130–152 (1954)
Wasserman, M.: Cytological studies of the repleta group of the genus Drosophila. IV. The hydei subgroup. Univ. Texas Publ. 6205, 73–83 (1962a)—V. The mulleri subgroup. Idem, 85–117 (1962b)
Author information
Authors and Affiliations
Additional information
Communicated by E. Hadorn
Rights and permissions
About this article
Cite this article
Frei, H. Intragenic recombination at the white locus of Drosophila hydei . Molec. Gen. Genet. 142, 105–117 (1975). https://doi.org/10.1007/BF00266093
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00266093