Summary
Griseofulvin induces metaphase arrest and polyploidization in plant cells in culture; after which a process of chromosome segregation follows. During this process spontaneous or induced recessive mutations become expressed through the formation of homozygotes or monosomics. This finding can be of use whenever the isolation of recessive mutations is needed and haploid culture is difficult.
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Communicated by P. Maliga
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Schiavo, F.L., Ronchi, V.N. & Terzi, M. Genetic effects of griseofulvin on plant cell cultures. Theoret. Appl. Genetics 58, 43–47 (1980). https://doi.org/10.1007/BF00264668
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DOI: https://doi.org/10.1007/BF00264668