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Kinetics of 2,4,6-trichlorophenol in different organs of the rat

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Abstract

The concentration of 2,4,6-trichlorophenol was measured in the blood and various other tissues of the rat after IP administration of the compound at 25 mg per kg body weight. The highest concentration, 329±117 nmol·g−1, was found in the kidney. Half-times were between 1.4 and 1.8 h in the blood, brain, fat, kidney, liver and muscle. The extent of conjugation of 2,4,6-trichlorophenol was also investigated by measuring total and free chlorophenol in the blood.

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Pekari, K., Boudène, C. & Aitio, A. Kinetics of 2,4,6-trichlorophenol in different organs of the rat. Arch Toxicol 59, 41–44 (1986). https://doi.org/10.1007/BF00263956

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  • DOI: https://doi.org/10.1007/BF00263956

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