Abstract
The 197HgCl2 renal uptake was measured in 70 patients in order to study the degree of the background activity and to determine the best correction method. The deduction of background activity was made: a) From a concentric perirenal region of interest with no additional correction. b) Using a double tracer technique with colloid 99mTc, subtracting consecutively the liver and spleen activity and the residual background.
Comparison of the results revealed: a) The correction of background activity significantly altered the uptake estimations, and thus must include both the liver and spleen activity, and the residual background. b) The choice of a median region of interest for the residual background evaluation led to a systematic error. c) The assessment of background activity, based upon a perirenal region of interest provided a sufficiently precise and reliable correction of the total background, while avoiding the inconveniences associated with the double tracer method.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Desgrez, A., Benhamou, J.P.: Foie. In: Traité de médecine nucléaire, G. Meyniel (Ed.), Vol. 2, pp. 168–183. Paris: Flammarion 1975
Erbsmann, F.: Problèmes posés par la scintigraphie quantitative à l'aide de la gamma caméra. Sensibilité et homogénéité. In: La fixation rénale du Mercure et du DMSA, C. Raynaud (Ed.), pp. 28–41. Orsay: Commissariat à l'Engergie Atomique 1976
Jacquot, C., Raynaud, C.: Précautions à prendre avec le foie, la rate et l'intestin. In: La fixation rénale du mercure radioactif (197 Hg Cl2), C. Raynaud (Ed.), pp. 52–57. Paris: Masson 1973
Koral, K.F., Sarkar, S.D.: An operator independent method for background subtraction in adrenal uptake measurements—Concise communication. J. Nucl. Med. 18, 925–928 (1977)
Leger, A., Reach, G., Lewin, F., Massin, J.P.: Comparison of two methods for the subtraction of liver and spleen activity in the evaluation of mercury bichloride renal uptake. Abstracts of the first Congress of Nuclear Medicine. Eur. J. Nucl. Med. 1, 72 (1976)
Raynaud, C., Desgrez, A., Kellershohn, C.: Exploration rénale à l'aide de la Néohydrine et du Bichlorure de Hg marqués aux mercures radio-actifs 197 Hg et 203 Hg. In: Radioaktive Isotopen in Klinik und Forschung. Vol. V, pp. 317–343. München/Berlin: Urban und Schwarzenberg 1963
Raynaud, C., Desgrez, A., Kellershohn, C.: Measurement of renal mercury uptake by external counting: separate functional testing of each kidney. J. Urol. 99, 248–263 (1968)
Raynaud, C., Ricard, S., Karam, Y., Kellershohn, C.: The use of the renal uptake of 197 Hg as a method for testing the functional value of each kidney. J. Nucl. Med. 11, 125–133 (1970)
Raynaud, C., Ricard, S.: Problème du fantome. In: La fixation rénale du mercure radioactif (197 Hg Cl2), C. Raynaud (ed.), pp. 49–51. Paris: Masson 1973
Raynaud, C., Jacquot, C., Freeman, L.M.: Measuring renal uptake of 197 Hg Cl2 by gamma camera. Radiology 110, 413–417 (1974)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Massin, JP. A single tracer method for background subtraction in 197HgCl2 renal uptake measurements. Eur J Nucl Med 4, 333–338 (1979). https://doi.org/10.1007/BF00263300
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00263300