Die Beziehungen zwischen Phosphatdurchtritt und Glucoseresorption

Summary

• 1. The dependence on temperature of phosphate penetration across the intestinal wall was higher (Q₁₀=5,3) than for the diffusing rhodanid (Q₁₀=1,7) and also higher than for the glucose transport (Q₁₀=3,0).

• 2. The phosphate flux from the mucosal to the serosal side was 2 to 3 times higher than in the opposite direction wherease the phosphate uptake into the tissue was the same for both directions.

• 3. Under anaerobic conditions or DNP, the phosphate flux from the mucosal to the serosal side rose about 2–3 times. In the opposite direction, the increase was very small and only significant under anaerobic conditions. The uptake into the intestinal tissue did not increase anaerobically.

• 4. The phosphate concentration in the fluid produced on the serosal side was 1,5 times, and the glucose concentration 1,8 times higher than in the mucosal fluid.

• 5. Azide, NaF and phlorrhizin activated the phosphate penetration. Iodoacetic acid had no influence. Further it did not inhibit the phosphate flux increased by DNP in spite of an inhibitionof glycolysis.

• 6. Phlorrhizin concentrations between 10⁻³ and 10⁻² mol increased the phosphate flux, whereas the glucose transport was already inhibited by concentrations between 10⁻⁶ and 10⁻⁵ mol.