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Soluble polymers in organic synthesis

3. Polyethylene glycol as acid labile solubilizing protecting group

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Summary

The end function of polyethylene glycol was transferred to the tertiary alcohol for use as acid labile, solubilizing protecting group in peptide synthesis.

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References

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  • Pillai, V.N.R. and Mutter, M.: Naturwissenschaften 68, 558 (1981)

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  • Pillai, V.N.R., Mutter, M., Bayer, E. and Gatfield, I.: J. Org. Chem. 45, 5364 (1980)

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For communication 2 in this series see: Mutter, M., Tetrahedron Letters, 2843 (1978)

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Anzinger, H., Mutter, M. Soluble polymers in organic synthesis. Polymer Bulletin 6, 595–601 (1982). https://doi.org/10.1007/BF00255161

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  • DOI: https://doi.org/10.1007/BF00255161

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