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Radiation risk of thyroid scintigraphy in newborns

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Abstract

Tumor risk factors were calculated for newborns who were investigated for congential hypothyroidism (CHT) with radionuclides by thyroid scintigraphy. Figures for three radiopharmaceuticals, 99mTc-pertechnetate, 123I-and 131I-sodium iodide for adults were extrapolated to newborns. The radiation dose to the normal thyroid gland in newborns was seven times higher for 123I-NaI than for 99mTcO -4 , the somatically effective total body dose was two times higher for 123I-NaI than for 99mTcO -4 . The use of 123I-NaI was preferred because of better scintigraphic results. Risk estimates for thyroid scintigraphy in newborns in the diagnostic work-up of CHT are given using published age-dependent tumor induction figures derived from atomic bomb survivors.

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Beekhuis, H., Piers, D.A. Radiation risk of thyroid scintigraphy in newborns. Eur J Nucl Med 8, 348–350 (1983). https://doi.org/10.1007/BF00253544

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  • DOI: https://doi.org/10.1007/BF00253544

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