Abstract
99mTc-human serum albumin microcolloid (HSAC) was evaluated for diagnosis of deep venous thrombosis (DVT) in the legs of 38 consecutive patients. Five and thirty minutes after IV injection, the 99mTc-HSAC activity in both legs was measured by external counting using a collimated NaI (Tl)-detector. The relative predominance of 99mTc-HSAC activity in the diseased leg was calculated. Phlebography was performed as a control after the 99mTc-HSAC test. In our hands the non-invasive 99mTc-HSAC test appeared to be rapid, easy to perform and convenient to the patient. The test showed a high sensitivity (11/13) and a low specificity (10/20) compared with phlebography. No adverse reactions were found. The results seem promising and further studies are in progress to establish the value of the 99mTc-HSAC test in screening for DVT.
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Edenbrandt, C.M., Andersson, L., Larsson, I. et al. Diagnosis of deep venous thrombosis by 99mTc-human serum albumin microcolloid. Eur J Nucl Med 8, 332–334 (1983). https://doi.org/10.1007/BF00253539
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DOI: https://doi.org/10.1007/BF00253539