Abstract
Single photon emission computed tomography (SPECT) has been shown to be of value in estimating the radiation dose to the peritoneum from 32P therapy. Simple dosimetry calculations, assuming uniform irradiation of tissue, indicate that radiation doses of ∼40 Gy to the peritoneal surface are achieved. However, the images show that the radionuclide distribution is non-uniform, giving rise to radiation dose variations of at least a factor of 10.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Boge E, Lindegaard MW, Pans E, Skretting A, Davy M, Jakobsen E (1984) Whole-body distribution of radioactivity after intraperitoneal administration of 32P colloids. Br J Radiol 57:395–402
Kaplan WD, Zimmerman RE, Bloomer WD, Knapp RC, Adelstein SJ (1981) Therapeutic intraperitoneal 32P: a clinical assessment of the dynamics of distribution. Radiology 138:683–688
Ott RJ, Flower MA, Jones A, McCready VR (1984) The application of SPECT to determine the radiation dose from P32-chromic phosphate therapy of the peritoneal cavity. Eur J Nucl Med 9:A22
Root SW, Tyor MP, Andrews GA, Kimsley RM (1954) Distribution of colloidal radioactive chromic phosphate after intracavitary administration. Radiology 63:251–259
Rosenhein NB, Leichner PK, Vogelsang G (1979) Radiocolloids in the treatment of ovarian cancer. Obstet Gynaecol Surv 34(9):708–720
Young MEJ (1985) Distribution of radioactivity after intra-peritoneal administration of 32P colloids. Br J Radiol 58:100–101
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ott, R.J., Flower, M.A., Jones, A. et al. The measurement of radiation doses from P32 chromic phosphate therapy of the peritoneum using SPECT. Eur J Nucl Med 11, 305–308 (1985). https://doi.org/10.1007/BF00252342
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00252342