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Experimentelle Beiträge zur Pathophysiologie des Klärfaktors

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Summary

  1. 1.

    In rats and rabbits, clearing factor activation by heparin injections regularly undergoes a transient reduction after liver damage by carbon tetrachloride. In the rat, an increased activity (spontaneous as well as subsequent to heparin activation) follows in a later phase.

  2. 2.

    In pregnant rats and rabbits, clearing factor activation is liable to be considerably reduced, although sometimes only temporarily. Normalization usually sets in several days before parturition.

  3. 3.

    Rabbits treated with estradiol, progesterone, and gonadotropic hormone showed normal clearing factor activation.

  4. 4.

    In some alloxan-diabetic rats and rabbits, reduction of clearing factor activation is observed.

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Literatur

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Authors and Affiliations

  1. Aus der Abteilung für experimentelle Medizin der F. Hoffmann-La Roche & Co. AG., Basel

    K. Reber & A. Studer

Authors
  1. K. Reber
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  2. A. Studer
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Reber, K., Studer, A. Experimentelle Beiträge zur Pathophysiologie des Klärfaktors. Naunyn - Schmiedebergs Arch 233, 384–392 (1958). https://doi.org/10.1007/BF00247417

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  • DOI: https://doi.org/10.1007/BF00247417

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