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Effects of fibroblast growth factor and bromocriptine on the mitotic activity of the anterior pituitary gland in organ culture

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Summary

Effects of fibroblast growth factor (FGF) and of bromocriptine, a dopaminergic receptor agonist, on the mitotic index in the organ-cultured anterior pituitary gland of the rat were investigated, using the colchicine metaphase-arrest technique. It has been found that FGF increases the mitotic index in the anterior pituitary explants. By contrast bromocriptine inhibits the mitogenic effect of FGF.

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Authors and Affiliations

  1. Department of Experimental Endocrinology, Institute of Endocrinology, School of Medicine, Łódź, Poland

    M. Pawlikowski & H. Stepień

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  1. M. Pawlikowski
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  2. H. Stepień
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Pawlikowski, M., Stepień, H. Effects of fibroblast growth factor and bromocriptine on the mitotic activity of the anterior pituitary gland in organ culture. Cell Tissue Res. 202, 165–169 (1979). https://doi.org/10.1007/BF00239229

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  • DOI: https://doi.org/10.1007/BF00239229

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