Summary
Cats received lesions that transected the entire thoracic cord except for partial sparing of the dorsal columns. The cats were required to discriminate the side on which they were touched, the size of simultaneously presented discs, or the direction their fur was stroked to obtain food reward. All cats found by anatomical and/or electrophysiological criteria to have any functional continuity in the dorsal columns were able to master the first of these tasks; some responded above chance on the second. Performance was at chance on blank trials, and cats with complete cord transection failed to discriminate. Lesioned cats did not orient or otherwise react to any nonrewarded stimulus below the level of the lesion. A total of 532 units were recorded under light barbiturate anesthesia from the hind paw projection near the tip of the ansate sulcus in these and other similarly prepared cats. Three-fourths of the units found before and acutely after the cord lesions were made were driven by hind limb stimulation. Only 27% of the units recorded 10 or more days afterwards could be driven. Of these driven units, 15 (38%) responded to foreleg stimulation, 13 exclusively so. No such units were found in intact or acutely lesioned cats.
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References
Andersson, S.A.: Suppression of cortical spontaneous barbiturate spindles via specific and unspecific projection spinal pathways. Acta physiol. scand. 69, 191–202 (1967)
Andersson, S.A., Leissner, P.: Development of spinal sensory pathways in the kitten. Presented at the Sixth International Meeting of Neurobiologists. Oxford 1972
Andersson, S.A., Leissner, P.: The thalamic representation for spinal ventral afferent pathways in kitten. Acta physiol. scand. 90, Suppl. 396, 109 (1973)
Angaut-Petit, D.: The dorsal column system: II. Functional properties and bulbar relay of the postsynaptic fibres of the cat's fasciculus gracilis. Exp. Brain Res. 22, 471–493 (1975)
Azulay, A., Schwartz, A.S.: The role of the dorsal funiculus of the primate in tactile discrimination. Exp. Neurol. 46, 315–332 (1975)
Baker, M.A., Tyner, C.F., Towe, A.L.: Observations on single neurons recorded in the sigmoid gyri of awake, non-paralyzed cats. Exp. Neurol. 32, 385–403 (1971)
Bava, A., Fadigia, E., Manzoni, T.: Deafferentazione cronica e proprietá funzionali dei nuclei talamici di relais somatico. Rend. Accad. naz. Lincei, Cl. Sci. fis. mat. nat. 40, Ser. VIII, 912–920 (1966a)
Bava, A., Fadigia, E., Manzoni, T.: Interactive potentialities between thalamic relay-nuclei through subcortical commissural pathways. Arch. Sci. biol. 50, 101–133 (1966b)
Beck, C.: Forelimb performance by squirrel monkeys (Saimiri sciureus) before and after dorsal column lesions. J. comp. physiol. Psychol. 90, 353–362 (1976)
Bowsher, D.: Projection of the gracile and cuneate nuclei in macaca mulatta: An experimental degeneration study. J. comp. Neurol. 110, 135–151 (1958)
Bowsher, D.: Properties of ventrobasal thalamic neurons in cats following interruption of specific afferent pathways. Arch. ital. Biol. 109, 59–74 (1971)
Chow, K.L.: Visual discrimination after extensive ablation of optic tract and visual cortex in cats. Brain Res. 9, 363–366 (1968)
Cook, A.W., Browder, E.J.: Function of the posterior columns in man. Arch. Neurol. (Chic.) 12, 72–79 (1965)
Dobry, P.J.K., Casey, K.L.: Roughness discrimination in cats with dorsal column lesions. Brain Res. 44, 385–397 (1972a)
Dobry, P.J. K., Casey, K.L.: Coronal somatosensory unit responses in cats with dorsal column lesions. Brain Res. 44, 399–416 (1972b)
Dubrovsky, B., Davelaar, E., Garcia-Rill, E.: The role of dorsal columns in serial order acts. Exp. Neurol. 33, 93–102 (1971)
Dubrovsky, B., Garcia-Rill, E.: Role of dorsal columns in sequential motor acts requiring precise forelimb projection. Exp. Brain Res. 18, 165–177 (1973)
Eidelberg, E., Kreinick, C.J., Langescheid, C.: On the possible functional role of afferent pathways in skin sensation. Exp. Neurol. 47, 419–432 (1975)
Fellows, B.J.: Chance stimulus sequences for discrimination tasks. Psychol. Bull. 67, 87–92 (1967)
Galambos, R., Norton, T.T., Frommer, G.P.: Optic tract lesions sparing pattern vision in cats. Exp. Neurol. 18, 8–25 (1967)
Gilman, S., Denny-Brown, D.: Disorders of movement and behavior following dorsal column lesions. Brain 89, 397–418 (1966)
Goldberg, J.M., Neff, W.D.: Frequency discrimination after bilateral section of the brachium of the inferior colliculus. J. comp. Neurol. 116, 265–284 (1961)
Harris, F.A.: Population analysis of somatosensory thalamus in the cat. Nature (Lond.) 225, 559–562 (1970)
Jabbur, S.J., Baker, M.A., Towe, A.L.: Wide-field neurons in thalamic nucleus ventralis posterolateralis of the cat. Exp. Neurol. 36, 213–238 (1972)
Levitt, J., Levitt, M.: Sensory hind-limb representation im Sm I cortex of the cat. A unit analysis. Exp. Neurol. 22, 259–275 (1968a)
Levitt, M., Levitt, J.: Sensory hind-limb representation in the Sm I cortex of the cat after spinal tractotomies. Exp. Neurol. 22, 276–302 (1968b)
Levitt, J., Levitt, M.: Postcentral somatic mechanoreception: I. Dorsal column and anterolateral lesions. Presented at the Fourth Annual Meeting, Society for Neuroscience, St. Louis, Mo. October 1974a
Levitt, M., Levitt, J.: Postcentral somatic mechanoreception: II. Dorsal quadrant, hemisection, and anterolateral lesions. Presented at the Fourth Annual Meeting, Society for Neuroscience, St. Louis, Mo. October 1974b
Lund, R.D., Webster, K.E.: Thalamic afferents from the spinal cord and trigeminal nuclei. An experimental anatomical study in the rat. J. comp. Neurol. 130, 313–327 (1967)
Mallart, A., Martinoya, C., Albe-Fessard, D.: Comparison entre les types de stimulations naturelles qui évoquent des réponses dans les relais spécifiques ou les relais associatifs. J. Physiol. (Paris) 53, 421–422 (1961)
Mallart, A., Petit, D.: Afferénces nonspécifiques conduit par les collatérales spinales de voies longue des cordons posterieurs. J. Physiol. (Paris) 55, 291–292 (1963)
Matzke, H.A.: The course of the fibers arising from the nucleus gracilis and cuneatus of the cat. J. comp. Neurol. 94, 439–452 (1951)
Melzack, R., Bridges, J.A.: Dorsal column contributions to motor behavior. Exp. Neurol. 33, 53–68 (1971)
Melzack, R., Southmayd, S.E.: Dorsal column contributions to anticipatory motor behavior. Exp. Neurol. 42, 274–281 (1974)
Merrill, E.G., Wall, P.D.: Factors forming the edge of a receptive field: The presence of relatively ineffective afferent terminals. J. Physiol. (Lond.) 226, 825–846 (1972)
Millar, J., Basbaum, A.I., Wall, P.D.: Restructuring of the somatotopic map and appearance of abnormal neuronal activity in the gracile nucleus after partial deafferentation. Exp. Neurol. 50, 658–672 (1976)
Morrillo, A., Baylor, D.: Electrophysiological investigation of the lemniscal and paralemniscal input to the midbrain reticular formation. Electroenceph. clin. Neurophysiol. 15, 455–464 (1963)
Myers, D.A., Hostetter, G., Bourassa, C.M., Swett, J.E.: Dorsal columns in sensory detection. Brain Res. 70, 350–355 (1974)
Pompeiano, O., Swett, J.E.: Identification of cutaneous and muscular afferent fibers producing EEG synchronization or arousal in normal cats. Arch. ital. Biol. 100, 343–380 (1962)
Schwartz, A.S., Eidelberg, E., Marchok, P., Azulay, A.: Tactile discrimination in the monkey after section of the dorsal funiculus and lateral lemniscus. Exp. Neurol. 37, 582–596 (1972)
Segal, S.: Nonparametric slatistics for the behavioral sciences. New York: McGraw-Hill (1956)
Shimazu, H., Yanagisawa, N., Garoutte, B.: Corticopyramidal influences on thalamic transmission in the cat. Jap. J. Physiol. 15, 101–124 (1965)
Spears, R., Smith, F., Casey, K.L.: A pulse height discriminator and post-stimulus histogram system using integrated circuits. Physiol. Behav. 5, 1327–1329 (1970)
Towe, A.L., Whitehorn, D., Nyquist, J.K.: Differential activity among wide-field neurons of the cat postcruciate cerebral cortex. Exp. Neurol. 20, 497–521 (1968)
Vierck, C.J. Jr.: Tactile movement detection and discrimination following dorsal column lesions in monkeys. Exp. Brain Res. 20, 331–346 (1974)
Wall, P.D.: The sensory and motor role of impulses travelling in the dorsal columns towards cerebral cortex. Brain 93, 505–524 (1970)
Wall, P.D., Dubner, R.: Somatosensory pathways. Ann. Rev. Physiol. 44, 315–336 (1972)
Wall, P.D., Egger, M.D.: Formation of new connexions in adult rat brains after partial deafferentation. Nature (Lond.) 232, 542–545 (1971)
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Frommer, G.P., Trefz, B.R. & Casey, K.L. Somatosensory function and cortical unit activity in cats with only dorsal column fibers. Exp Brain Res 27, 113–129 (1977). https://doi.org/10.1007/BF00237693
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DOI: https://doi.org/10.1007/BF00237693