Summary
The ultrastructure of cat abducens motoneurones is described, after labelling by retrograde axonal transport of horseradish peroxydase. The motoneurones were densely covered with synaptic boutons of both the “terminal” and “en passant” types and axo-axonal synapses were observed on the initial segment of motoneurone axons. Within the population of axons forming the VIth nerve, multiple branching was encountered and axons closely apposed at the nodes of Ranvier were seen.
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Baker, R., Highstein, S.M.: Physiological identification of interneurons and motoneurons in the abducens nucleus. Brain Res. 91, 292–298 (1975)
Conradi, S.: On motoneuron synaptology in cats and kittens. An electron microscopic study of the structure and location of neuronal and glial elements on cat lumbosacral motoneurons in the normal state and after dorsal root section. Acta physiol. scand. Suppl. 00, 332–333 (1969)
Gacek, R.R.: Anatomical demonstration of the vestibulo-ocular projections in the cat. Acta otolaryng. (Stockh.) 293, 1–63 (1971)
Gacek, R.R.: Localization of neurons supplying the extraocular muscles in the kitten using horseradish peroxidase. Exp. Neurol. 44, 381–403 (1974)
Gogan, P., Grant, K., Tyć-Dumont, S.: Multiple axonal excitation following intracellular stimulation of single abducens motoneurones. J. Physiol. (Lond.) 256, 11P-12P (1976)
Gogan, P., Gueritaud, J.P., Horcholle-Bossavit, G., Tyć-Dumont, S.: Inhibitory nystagmic interneurons. Physiological and anatomical identification within the abducens nucleus. Brain Res. 59, 410–416 (1973)
Graybiel, A.M., Hartwieg, E.A.: Some afferent connections of the oculomotor complex in the cat: an experimental study with tracer techniques. Brain Res. 81, 543–551 (1974)
Grossman, Y., Spira, M.E., Parnas, N.I.: Differential flow of information into branches of a single axon. Brain Res. 64, 379–386 (1973)
Hatt, H., Smith, D.O.: Axon conduction block: differential channeling of nerve impulse in the crayfish. Brain Res. 87, 85–88 (1975)
Horcholle-Bossavit, G., Tyć-Dumont, S.: Phénomènes synaptiques du nystagmus. Exp. Brain Res. 8, 201–218 (1969)
Maciewicz, R.J., Kaneko, C.R.S., Highstein, S.M., Baker, R.: Morpholo-physiological identification of interneurons in the oculomotor nucleus that project to the abducens nucleus in the cat. Brain Res. 96, 60–65 (1975)
Nauta, H.J.W., Pritz, M.B., Lasek, R.J.: Afferents to the rat caudoputamen studied with horseradish peroxidase. An evaluation of a retrograde neuro-anatomical research method. Brain Res. 67, 219–238 (1974)
Palay, S.L.: The structural basis for neural action. In: Brain function, Vol. 2, RNA and brain function; memory and learning (ed. M.A.B. Brazier). Berkeley: University of California Press 1964
Peters, A., Proskauer, C.C., Kaiserman-Abramof, I.R.: The small pyramidal neuron of the rat cerebral cortex. The axon hillock and initial segment. J. Cell Biol. 39, 604–619 (1968)
Ramón y Cajal, S.: Histologie du système nerveux de l'homme et des vertébrès. Paris: Maloine 1909
Sotelo, C., Palay, S.L.: The fine structure of the lateral vestibular nucleus in the rat. I. Neurons and neuroglial cells. J. Cell Biol. 36, 151–179 (1968)
Szentágothai, J.: Pathways and synaptic articulation patterns connecting vestibular receptors and oculomotor nuclei. In: The oculomotor system (ed. M.B. Bender). New York: Hoeber 1964
Tarlov, E., Tarlov, S.R.: Representation of extraocular muscles in oculomotor nuclei: experimental studies in cat. Brain Res. 34, 37–52 (1971)
Waxman, S.G.: Regional differentiation of the axon: a review with special reference to the concept of the multiplex neuron. Brain Res. 47, 269–288 (1972)
Waxman, S.G.: Ultrastructural observations on branching patterns of central axons. Neuroscience Lett. 1, 251–256 (1975)
Waxman, S.G., Pappas, G.D.: An electron microscope study of synaptic morphology in the oculomotor nuclei of three inframammalian species. J. comp. Neurol. 143, 41–72 (1971)
Westrum, L.E.: Synaptic contacts on axons in the cerebral cortex. Nature (Lond.) 210, 1289–1290 (1966)
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This work was supported by I.N.S.E.R.M. (U 6), C.N.R.S. (GR 25) and RCP 391 from the C.N.R.S.
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Destombes, J., Ripert, J.P. Ultrastructural observations of the abducens nucleus of the cat after injection of horseradish peroxydase into the lateral rectus muscle. Exp Brain Res 28, 63–71 (1977). https://doi.org/10.1007/BF00237086
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DOI: https://doi.org/10.1007/BF00237086