Summary
Brain slices from adult and newborn rats were incubated with [35S]taurine in Krebs-Ringer bicarbonate medium at pH 7.4. In both age groups electrical stimulation increased the oxygen consumption of the slices. The influx of taurine only increased in slices from adult rats. The influx conformed to Michaelis-Menten kinetics. In slices from adult rat Vmax increased and apparent Km remained unchanged during electrical stimulation. Both Km and Vmax were greater in adult than in newborn rats. The efflux of taurine from slices depended on the intracellular concentration of taurine and was not measurably influenced by electrical stimulation.
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Lähdesmäki, P., Oja, S.S. Effect of electrical stimulation on the influx and efflux of taurine in brain slices of newborn and adult rats. Exp Brain Res 15, 430–438 (1972). https://doi.org/10.1007/BF00234128
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DOI: https://doi.org/10.1007/BF00234128