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(2′–5′) Oligoadenylate synthetase in the maturation of rabbit reticulocytes

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Summary

The (2′–5′) oligoadenylate synthetase normally found in interferon-treated cells has also been detected in considerable amounts in normal rabbit reticulocytes not exposed to interferon. The activity of this enzyme has been followed during the development of the reticulocytes to erythrocytes.

A high level was found just after the formation of reticulocytes and this activity decayed with a half-life of about 3 days. In lymphocytes the (2′–5′) oligoadenylate synthetase was found to stay at a constant level, which indicates the absence of interferon in the plasma.

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References

  1. Lengyel, P., 1982. Ann. Rev. Biochem. 51: 251–282.

    Google Scholar 

  2. Kerr, I. M. and Brown, R. E., 1978. Proc. Natl. Acad. Sci. U.S.A. 75: 256–260.

    Google Scholar 

  3. Ball, L. A. and White, C. N., 1978. Proc. Natl. Acad. Sci. U.S.A. 75: 1167–1171.

    Google Scholar 

  4. Justesen, J., Ferbus, D. and Thang, M. N., 1980. Proc. Natl. Acad. Sci. U.S.A. 77: 4618–4622.

    Google Scholar 

  5. Justesen, J., Ferbus, D. and Thang, M. N., 1980. Nucl. Acids Res. 8: 3073–3085.

    Google Scholar 

  6. Cayley, P. J. and Kerr, I., 1982. Eur. J. Biochem. 122: 601–608.

    Google Scholar 

  7. Ferbus, D., Justesen, J., Besançon, F. and Thang, M. N., 1981. Biochem. Biophys. Res. Commun. 100: 847–856.

    Google Scholar 

  8. Stark, G. R., Dower, W. J., Schimke, R. J., Brown, R. E. and Kerr, I. M., 1979. Nature (London) 278: 471–473.

    Google Scholar 

  9. Silverman, R. H., Cayley, P. J., Knight, M., Gilbert, C. S. and Kerr, I. M., 1982. Eur. J. Biochem. 124: 131–138.

    Google Scholar 

  10. Thang, M. N., Ferbus, D., Besançon, F., Bourgeade, M. F. and Justesen, J., 1981 In: The Biology of the Interferon system (de Maeyer, E., Galasso, G. and Schellekens, H., eds), pp. 129–134. Elsevier/North Holland Biomedical Press Amsterdam.

  11. Hovanessian, A. G. and Kerr, I. M., 1978. Eur. J. Biochem. 84:149–159.

    Google Scholar 

  12. Baglioni, C., Minks, M. A. and Maroney, P. A., 1978. Nature (London) 273: 684–687.

    Google Scholar 

  13. Ball, L. A. and White, C. N., 1979. Virology 93: 348–356.

    Google Scholar 

  14. Schmidt, A., Zilberstein, A., Shulman, L., Federman, P., Berissi, H. and Revel, M., 1978. FEBS Lett. 95: 257–264.

    Google Scholar 

  15. Williams, B. R. G., Gilbert, C. S. and Kerr, I. M., 1979. Nucl. Acids Res. 6: 335–1350.

    Google Scholar 

  16. Hovanessian, A. G., Wood, I., Meurs, E. and Montagnier, L., 1979. Proc. Natl. Acad. Sci. U.S.A. 76: 3261–3265.

    Google Scholar 

  17. Randerath, E. and Randerath, K., 1967. J. Chromatogr. 31: 485–499.

    Google Scholar 

  18. Borsook, H., Deusy, C. L., Haagen-Smit, A. L., Keighley, G. and Lowy, P. H., 1952. J. Biol. Chem. 196: 669–694.

    Google Scholar 

  19. Boyum, A., 1968. Scand. J. Clin. Lab. Invest. 21, Suppl. 97.

    Google Scholar 

  20. Bender, E., West, C. and Blume, K. G., 1976. J. Lab. Clin. Med. 88: 328–333.

    Google Scholar 

  21. Drabkin, D. L., 1946. J. Biol. Chem. 112: 703–723.

    Google Scholar 

  22. Spector, T., 1978. Anal. Biochem. 86: 142–146.

    Google Scholar 

  23. Borsook, H., Lingrel, J. B., Scaro, R. L. and Millette, R., 1962. Nature 196: 347–350.

    Google Scholar 

  24. Smith, D. W. E. and Weinberg, W. C., 1981. Biochim. Biophys. Acta 655: 195–198.

    Google Scholar 

  25. Baglioni, C. and Maroney, P. A., 1980. J. Biol. Chem. 255: 8390–8393.

    Google Scholar 

  26. Krishnan, I. and Baglioni, C., 1981. Virology 111: 666–670.

    Google Scholar 

  27. Lab, M., Thang, M. N., Soteriadou, K., Koehren, F. and Justesen, J., 1982. Biochem. Biophys. Res. Commun. 105: 412–418.

    Google Scholar 

  28. West, D. K. and Ball, L. A., 1982. Mol. Cell Biol. 2: 1436–1443.

    Google Scholar 

  29. Zehavi-Willner, T. and Danon, D., 1971. Biochim. Biophys. Acta 238: 439–446.

    Google Scholar 

  30. Lodish, H. F. and Small, B., 1976. Cell 7: 59–65.

    Google Scholar 

  31. Hulca, S. A. and Arnstein, H. R. V., 1977. Biochim. Biophys. Acta 476: 131–148.

    Google Scholar 

  32. Wreschner, D. H., Silverman, R. H., James, T. C., Gilbert, C. S. and Kerr, I. M., 1982. Eur. J. Biochem. 124: 261–268.

    Google Scholar 

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Ferbus, D., Justesen, J., Bertrand, H. et al. (2′–5′) Oligoadenylate synthetase in the maturation of rabbit reticulocytes. Mol Cell Biochem 62, 51–55 (1984). https://doi.org/10.1007/BF00230077

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  • DOI: https://doi.org/10.1007/BF00230077

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