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Fibroblast and epidermal growth factors: their uses in vivo and in vitro in studies on cell functions and cell transplantation

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Summary

The events which led to the isolation of the fibroblast growth factor are described. Its impact on the development of new cell models which have been used for studies as diverse as the control of cell proliferation, cell differentiation, and cell transplantation have been reviewed.

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References

  1. Carnot, P. and Deflandre, L., 1906. CR Acad. Sci. 143, 432–434.

    Google Scholar 

  2. Channing, C. P., 1970. Rec. Prog. Horm. Res. 26, 589–603.

    Google Scholar 

  3. Gospodarowicz, D. and Gospodarowicz, F., 1972. Endocrinology 90, 1427–1446.

    Google Scholar 

  4. Gospodarowicz, D. and Gospodarowicz, F., 1972. Exptl. Cell Res. 75, 353–379.

    Google Scholar 

  5. Masui, H. and Garren, L. D., 1971. Proc. Natl. Acad. Sci. USA 68, 3206–3210.

    Google Scholar 

  6. Ramachadran, J. and Suyama, A. T., 1975. Proc. Natl. Acad. Sci. USA 72, 113–117.

    Google Scholar 

  7. Biskind, M. S. and Biskind, G. S., 1944. Proc. Soc. Exp. Biol. Med. 58, 176–179.

    Google Scholar 

  8. Furth, J. and Sobel, H., 1947. J. Natl. Cancer Inst. 8, 7–16.

    Google Scholar 

  9. Clark, J. F., Jones, K. L., Gospodarowicz, D. and Sato, G. H., 1972. Nature New Biol. 236, 180–183.

    Google Scholar 

  10. 10.Gospodarowicz, D., 1972. J. Biol. Chem. 247, 6491–6702.

    Google Scholar 

  11. Gospodarowicz, D., Jones, K. L. and Sato, G. H., 1974. Proc. Natl. Acad. Sci. USA 71, 2295–2299.

    Google Scholar 

  12. Jones, K. L. and Gospodarowicz, D., 1974. Proc. Natl. Acad. Sci. USA 71, 3372–3376.

    Google Scholar 

  13. Holley, R. W. and Kiernan, J. A., 1968. Proc. Natl. Acad. Sci. USA 60, 300–304.

    Google Scholar 

  14. Corvol, M. T., Malemud, C. J. and Sokoloff, L., 1972. Endocrinology 90, 262–271.

    Google Scholar 

  15. Armelin, H. A., 1973. Proc. Natl. Acad. Sci. USA 70, 2702–2706.

    Google Scholar 

  16. Gospodarowicz, D., 1974. Nature 249, 123–127.

    Google Scholar 

  17. Gospodarowicz, D., 1975. J. Biol. Chem. 250, 2515–2521.

    Google Scholar 

  18. Gospodarowicz, D. and Thakral, T. K., 1978. Proc. Natl. Acad. Sci. USA 75, 847–851.

    Google Scholar 

  19. Carrel, A. and Baker, L. E., 1926. J. Exp. Med. 44, 505–521.

    Google Scholar 

  20. Gospodarowicz, D. and Moran, J., 1974. Proc. Natl. Acad. Sci. USA 71, 4584–4588.

    Google Scholar 

  21. Gospodarowicz, D. and Moran, J., 1974. Proc. Natl. Acad. Sci. USA 71, 4648–4672.

    Google Scholar 

  22. Gospodarowicz, D. and Moran, J., 1974. Exptl. Cell Res. 90, 279–288.

    Google Scholar 

  23. Gospodarowicz, C., Greene, G. and Moran, J. H., 1975. Biochem. Biophys. Res. Comm. 62, 779–785.

    Google Scholar 

  24. Rudland, P. S., Seifert, W. E. and Gospodarowicz, D., 1974. Proc. Natl. Acad. Sci. USA 71, 2600–2604.

    Google Scholar 

  25. Rudland, P. S., Eckhart, W., Gospodarowicz, D. and Seifert, W., 1974. Nature 250, 337–340.

    Google Scholar 

  26. 1972. The American Type Culture Collection. Registry of Animal Cell Lines (Shannon, J. E. and Mary, M. L., eds.), p. CCL92.

  27. Todaro, G. J. and Green, H. J., 1963. J. Cell Biol. 17, 299–307.

    Google Scholar 

  28. Gospodarowicz, D. and Moran, J. S., 1975. J. Cell Biol. 66, 451–458.

    Google Scholar 

  29. Gospodarowicz, D., Moran, J. and Owashi, N., 1977. J. Clin. Endocrinol. Metab. 44, 651–659.

    Google Scholar 

  30. Gospodarowicz, D. and Moran, J. S., 1977. Cell Culture and its Application (Acton, R. T. and Lynn, J. D., eds.), pp. 55–81, Academic Press, New York.

  31. Singer, M., 1952. Quart. Rev. Biol. 27, 169–200.

    Google Scholar 

  32. Singer, M., 1974. Ann. N.Y. Acad. Sci. 228, 308–322.

    Google Scholar 

  33. Gospodarowicz, D., Rudland, P., Lindstrom, J. and Benirschke, K., 1975. Advances in Metabolic Disorders (Luft, H., ed.), Vol. 8, p. 302, Stockholm.

  34. Gospodarowicz, D., Mescher, A. L. and Moran, J., 1978. Molecular Control of Proliferation and Cytodifferentiation. 35th Symposium of the Society for Developmental Biology (Papaconstantinou, J. and Butter, W. J., eds.), pp. 33–61, Academic Press, New York.

    Google Scholar 

  35. Hay, E. D., 1966. Regeneration, Holt, Rinehart, and Winston, New York.

    Google Scholar 

  36. Gospodarowicz, D., Weseman, J., Moran, J. and Lindstrom, J., 1976. J. Cell Biol. 70, 395.

    Google Scholar 

  37. Gospodarowicz, D., Moran, J. and Bialecki, H., 1976. Third Int. Symp. on Growth Hormone and Related Peptides, Excerpta Medica, p, 141, Amsterdam, The Netherlands.

    Google Scholar 

  38. Gospodarowicz, D. and Mescher, A. L., 1977. J. Cell Physiol. 93, 117–128.

    Google Scholar 

  39. Gospodarowicz, D., Weseman, J. and Moran, J., 1975. Nature 256, 216–219.

    Google Scholar 

  40. Gospodarowicz, D., 1976. Progr. in Clin. and Biol. Res. Membranes and Neoplasia: New Approaches and Strategies (Marchesi, V. T., ed.), pp. 1–19, A. R. Liss Inc., New York.

  41. Gospodarowicz, D. and Moran, J., 1976. Ann. Rev. Biochem., v. 45, p. 531.

    Google Scholar 

  42. Gospodarowicz, D. and Handley, H., 1975. Endocrinology 97, 102–116.

    Google Scholar 

  43. Gospodarowicz, D., Ill, C. R., Hornsby, P. J. and Gill, G. N., 1977. Endocrinology 100, 1080–1088.

    Google Scholar 

  44. Gospodarowicz, D., Ill, C. R., Mescher, A. L. and Moran, J., 1976. Fifth Int. Cong. of Endocrinology, Hamburg, Excerpta Medica, pp. 196–205, Elsevier, New York.

    Google Scholar 

  45. Fornero, A., 1931. Monitore Ostetr. Genec. 3, 3–31.

    Google Scholar 

  46. Gospodarowicz, D., Ill, C. R. and Birdwell, C. R. 1977. Endocrinology 100, 1108.

    Google Scholar 

  47. Gospodarowicz, D., and Bialecki, H., 1979. Endocrinology, 104, 722–730.

    Google Scholar 

  48. Gospodarowicz, D., Vlodavsky, I., Bialecki, H. and Brown, K., 1978. Fifth Brook Lodge Meeting on Novel Aspects of Reproductive Biology (Wilkes, J., ed.), pp. 107–178, Plenum Press.

  49. Gospodarowicz, D., Ill, C. R. and Birdwell, C. R., 1977. Endocrinology 100, 1121–1129.

    Google Scholar 

  50. Vlodavsky, I., Brown, K. and Gospodarowicz, D., 1978. J. Biol. Chem. 253, 3744–3750.

    Google Scholar 

  51. Gospodarowicz, D. and Bialecki, H., 1978. Endocrinology 103, 854–865.

    Google Scholar 

  52. Folkman, J., 1975. Cancer: A Comprehensive Treatise: Biology of Tumors, Cellular Biology, and Growth (Becker, F. F., ed.), pp. 355–388, Plenum Press, New York.

  53. Boone, C. W., Takeichi, N. and Paranjpe, M., et al., 1976. Cancer Res. 36, 1626–1633.

    Google Scholar 

  54. Jaffe, E. A., Nachman, R. L. and Becker, C. G., 1972. J. Clin. Invest. 51, 46a.

    Google Scholar 

  55. Gimbrone, M. A., Cotran, R. S. and Folkman, J., 1974. J. Cell Biol. 60, 673–684.

    Google Scholar 

  56. Gospodarowicz, D., Moran, J., Braun, D. and Birdwell, C. R., 1976. Proc. Natl. Acad. Sci. USA 73, 4120–4124.

    Google Scholar 

  57. Gospodarowicz, D., Moran, J. and Braun, D., 1977. J. Cell Physiol. 91, 377–390.

    Google Scholar 

  58. Gospodarowicz, D. and Zetter, B., 1977. Joint WHO/IABS Symposium on the Standardization of Cell Substrates for the Production of Virus Vaccine, pp. 109–129, S. Karger, Switzerland.

    Google Scholar 

  59. Zetter, B. R. and Gospodarowicz, D., 1977. Chemistry and Biology of Thrombin (Lunblad, R. L., Fenton, J. W. and Mann, K. G., eds.), pp. 551–560, Ann Arbor Press.

  60. Gospodarowicz, D., Greenburg, G., Bialecki, H. and Zetter, B., 1978. In Vitro, v. 14, 85–90.

    Google Scholar 

  61. Gospodarowicz, D., Brown, K. S., Birdwell, C. R. and Zetter, B. R., 1978. J. Cell Biol. 77, 774–779.

    Google Scholar 

  62. Gimbrone, M. A., Cotran, R. S., Leapman, S. B. and Folkman, J., 1974. J. Natl. Cancer Inst. 52, 413–427.

    Google Scholar 

  63. Gospodarowicz, D., Mescher, A. L. and Birdwell, C. R., 1978. Gene Expression and Regulation in Cultured Cells, Third Decennial Review Conference, National Cancer Institute Monographs, no. 48, pp. 109–131.

  64. Gospodarowicz, D., Mescher, A. L. and Birdwell, C. R., 1977. Exp. Eye Res. 25, 75–89.

    Google Scholar 

  65. Gospodarowicz, D. and Greenburg, G., 1979. Exptl. Cell Res., in press.

  66. Frati, I., Danieli, S., Delogu, A., and Covelli, I., 1972. Exp. Eye Res. 14, 135–141.

    Google Scholar 

  67. Savage, C. R. and Cohen, S., 1973. Exp. Eye Res. 15, 361–366.

    Google Scholar 

  68. Gospodarowicz, D., Mescher, A. L., Brown, K. and Birdwell, C. R., 1977. Exp. Eye Res. 25, 631–649.

    Google Scholar 

  69. Gospodarowicz, D., Greenburg, G. and Birdwell, C. R., 1978. Cancer Research, 38, 4155–4171.

    Google Scholar 

  70. Gospodarowicz, D., Bialecki, H. and Greenberg, G., 1978. J. Biol. Chem. 253, 3736–3743.

    Google Scholar 

  71. Westfall, F. C., Lennon, V. A. and Gospodarowicz, D., 1978. Proc. Natl. Acad. Sci. USA 75, 4675–4678.

    Google Scholar 

  72. Westermark, B. and Wasteson, A., 1975. Adv. Metab. Disord. 8, 85–100.

    Google Scholar 

  73. Gospodarowicz, D., Vlodavsky, I., Greenburg, G. and Johnson, L. K., 1979. Cold Spring Harbor Conferences: Hormones and Cell Culture (Ross, R. and Sato, G., ed.), Cold Spring Harbor, New York, in press.

  74. Gospodarowicz, D., Vlodavsky, I., Alvarado, J., Johnson, L. K. and Moran, J., 1979. Rec. Progr. in Hormone Res., v. 35, in press.

  75. Gospodarowicz, D., Greenburg, G., Vlodavsky, I., Alvarado, J. and Johnson, L. K., 1979. Exptl. Eye Res., in press.

  76. Birdwell, C. R., Gospodarowicz, D. and Nicholson, G., 1978. Proc. Natl. Acad. Sci. USA 75, 3273–3277.

    Google Scholar 

  77. Zetter, B. R., Martin, G. R. and Gospodarowicz, D., 1978. Annals of the N.Y. Acad. of Sciences 312, 299–316.

    Google Scholar 

  78. Zetter, B. R., Johnson, L. K., Shuman, M. and Gospodarowicz, D., 1978. Cell 14, 501–509.

    Google Scholar 

  79. Vlodavsky, I., Johnson, L. K. and Gospodarowicz, D., 1979. Proc. Natl. Acad. Sci. USA, June.

  80. Vlodavsky, I., Fielding, P., Fielding, C. and Gospodarowicz, D., 1978. Proc. Natl. Acad. Sci. USA 75, 356–360.

    Google Scholar 

  81. Gospodarowicz, D., Vlodavsky, I., Fielding, P. and Birdwell, C. R., 1978. Birth Defects (Littlefield, J. W. and de Grouchy, J., eds.), Excerpta Medica, pp. 233–271, Amsterdam, The Netherlands.

  82. Fielding, P. E., Vlodavsky, I., Gospodarowicz, D. and Fielding, C. J., 1979. J. Biol. Chem., 254, 749–755.

    Google Scholar 

  83. Vlodavsky, I., Johnson, L. K., Fielding, P. and Gospodarowicz, D., 1979, Cell, J. Cell. Physiol., in press.

  84. Goldminz, D., Vlodavsky, I., Johnson, L. K. and Gospodarowicz, D., 1979. Exptl. Eye Res., in press.

  85. Wessels, N. K., 1964. Proc. Natl. Acad. Sci. USA 52, 252–259.

    Google Scholar 

  86. Folkman, J. and Greenspan, H. P., 1975. Biochim. Biophys. Acta 417, 211–236.

    Google Scholar 

  87. Liu, Su-chin. and Karasek, 1978. J. Inv. Derm., in press. 71, 157–162.

    Google Scholar 

  88. Rheinwald, J. C. and Green, H., 1977. Nature 233, 421–424.

    Google Scholar 

  89. Grobstein, C. 1953. Nature 172, 869–873.

    Google Scholar 

  90. Grobstein, C., 1975. Extracellular Matrix Influences on Gene Expression (Slarkin, H. C. and Grenlich, R. C., eds.), pp. 9–16, Academic Press, New York.

  91. Hay, E. D., 1977. International Cell Biology (Brinkley, B. R. and Porter, K. R., eds.), pp. 50–57, Rockefeller Univ. Press, New York.

  92. Gospodarowicz, D. and Greenburg, G., 1979. Exptl. Eye Res., in press.

  93. Gospodarowicz, D. and Greenburg, G., 1979. Exptl. Eye Res., in press.

  94. Gospodarowicz, D., Greenburg, G. and Alvarado, J., 1979. Proc. Natl. Acad. Sci. USA, 76, 464–468.

    Google Scholar 

  95. Gospodarowicz, D., Greenburg, G. and Alvarado, J., 1979. Archives of Ophthalmol., in press.

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  1. Cancer Research Institute, M 1282, University of California, Medical Center, 94143, San Francisco, Ca., USA

    Denis Gospodarowicz

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Gospodarowicz, D. Fibroblast and epidermal growth factors: their uses in vivo and in vitro in studies on cell functions and cell transplantation. Mol Cell Biochem 25, 79–110 (1979). https://doi.org/10.1007/BF00228991

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