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The pineal gland of the mole-rat (Spalax ehrenbergi, Nehring)

I. The fine structure of pinealocytes

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Summary

The ultrastructure of pinealocytes of the mole-rat (Spalax ehrenbergi), a blind subterranean mammal living in complete darkness, was examined and compared with pinealocytes of other mammals. Two different populations of pinealocytes (I and II) were observed. They differed in general aspect, in location and especially in their content of cell organelles involved in synthetic processes. Mitochondria, ribosomes, granular endoplasmic reticulum, lysosomes, lipid inclusions and glycogen granules were present in the perikarya of pinealocytes of both populations. In the pinealocyte of population I some granular vesicles were occasionally observed in the cell body. Their presumed origin from the Golgi apparatus could not be clearly demonstrated. In the perikaryon of this pinealocyte, concentrations of ribosomes and of cisternae of the granular endoplasmic reticulum were constantly observed. These concentrations may indicate an intensive synthetic activity. Pinealocytes of population II were characterized by accumulations of proteinaceous material in some cisternae of the granular endoplasmic reticulum and between the two layers of the nuclear membrane. The origin of these peculiar elements is discussed.

Résumé

Les pinéalocytes de la glande pinéale du Spalax ehrenbergi (animal ayant un appareil visuel atrophié et vivant toujours dans une obscurité complète) examinés au microscope électronique ont été comparés à ceux d'autres Mammifères. Deux populations de pinéalocytes (I and II) ont été observées. Elles diffèrent par la localisation dans la glande, l'aspect du noyau et l'aspect sécrétoire des pinéalocytes. Mitochondries, ribosomes, réticulum endoplasmic granulaire, structures lysosomiales, inclusions lipidiques et grains de glycogène sont présents dans le périkaryon des deux populations de pinéalocytes. De rares grains de sécrétion furent observés dans le corps cellulaire des pinéalocytes I, leur origine golgienne, probable, n'a pu encore être démontrée. De plus, dans le périkaryon de ce type de pinéalocytes des concentrations de ribosomes et de citernes du réticulum endoplasmique granulaire furent toujours observées. La présence d'une accumulation de matériel protéique dans quelques citernes du réticulum endoplasmique granulaire et entre les deux feuillets de l'enveloppe nucléaire est caractéristique des pinéalocytes II. L'origine de ces élements particuliers est discutée.

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Authors and Affiliations

  1. The Netherlands Central Institute for Brain Research, Amsterdam, The Netherlands

    Paul Pevet, J. Ariëns Kappers & Eviatar Nevo

  2. Biological Laboratory, University of Haifa, 31, Haifa, Israel

    Eviatar Nevo

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  1. Paul Pevet
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  2. J. Ariëns Kappers
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  3. Eviatar Nevo
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This paper is dedicated in great admiration and appreciation to Prof. Dr. Berta Scharrer on the occasion of her 70th birthday

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Pevet, P., Kappers, J.A. & Nevo, E. The pineal gland of the mole-rat (Spalax ehrenbergi, Nehring). Cell Tissue Res. 174, 1–24 (1976). https://doi.org/10.1007/BF00222147

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