Summary
Prolactin cells from anterior pituitary glands of normal non-lactating female rats, and lactating animals, some of which were separated from their pups for 48 hours, were examined ultrastructurally for the presence of microfilaments. Microfilaments were found in specific intracellular locations in all cells examined. They were in association with the nuclear envelope, the Golgi complex, the endoplasmic reticulum, small vesicles of the endoplasmic reticulum, and secretory granules. The possible role of microfilaments in the movement of intracellular organelles is considered.
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This investigation was supported by the National Institutes of Health grants AM 12583 and TW 02023.
The authors wish to express their gratitude to Mr. M. G. Williams and Miss Pauline Cisneros for their excellent technical assistance.
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Warchol, J.B., Herbert, D.C. & Rennels, E.G. Localization of microfilaments in prolactin cells of the rat anterior pituitary gland. Cell Tissue Res. 155, 193–199 (1974). https://doi.org/10.1007/BF00221353
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DOI: https://doi.org/10.1007/BF00221353