Summary
The slow soleus muscle grafted into the bed of the fast, highly androgen sensitive levator ani (LA) muscle and innervated by the pudendal nerve, originally innervating the LA muscle acquires contraction and histochemical properties of the fast LA muscle. However, the “cross-transplanted” soleus muscle shows no changes in weight, contraction and histochemical properties after castration and testosterone application of 2 months duration. Thus the grafted soleus muscle is transformed into a fast muscle by foreign innervation, it does, however, not acquire androgen sensitivity, the latter being apparently primarily of myogenic origin.
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Hanzlíková, V., Gutmann, E. The absence of androgen-sensitivity in the grafted soleus muscle innervated by the pudendal nerve. Cell Tissue Res. 154, 121–129 (1974). https://doi.org/10.1007/BF00221076
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DOI: https://doi.org/10.1007/BF00221076