Summary
Application of horseradish peroxidase into the posterior thalamic and basal optic neuropils of Salamandra salamandra (L.) revealed strong reciprocal connections between the pretectum and the accessory optic system. Pretectal neurons located within the periventricular gray matter project to the basal optic neuropil distributing their terminals over the whole extent of this neuropil. A well developed nucleus of the basal optic neuropil, with its neurons within and medial to this neuropil, projects to the posterior thalamic neuropil. Its terminals appear to be located selectively within the core of the posterior thalamic neuropil which receives no ipsilateral retinal afferents.
The pretectum and the accessory optic system are reciprocally connected to a ventral tegmental nucleus, which has not previously been described in urodeles. This nucleus is located immediately dorsal to the oculomotor and trochlear nuclei and extends from the oculomotor root to the middle of the trochlear nucleus.
Dendrites of the nucleus of Darkschewitsch reach the posterior thalamic neuropil but mainly enter the rostral tegmental neuropil, while the dendrites of the nucleus of the medial longitudinal fasciculus ramify within the basal optic neuropil and the anterior tegmental neuropil with minor branches in the caudal posterior thalamic neuropil.
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References
Berson DM, Graybiel AM (1980) Some cortical and subcortical fiber projections to the accessory optic nuclei in the cat. Neuroscience 5:2203–2217
Blanks RHI, Giolli RA, Pham SV (1982) Projections of the medial terminal nucleus of the accessory optic system upon pretectal nuclei in the pigmented rat. Exp Brain Res 48:228–237
Brecha N, Karten HJ, Hunt SP (1980) Projections of the nucleus of the basal optic root in the pigeon: An autoradiographic and horseradish peroxidase study. J Comp Neurol 189:615–670
Cochran G, Dieringer N, Precht W (1984) Basic optokinetic-ocular reflex pathway in the frog. J Neurosci 4:43–57
Collewijn H (1975) Oculomotor areas in the rabbit's midbrain and pretectum. J Comp Neurol 6:3–22
Collewijn H (1980) Sensory control of optokinetic nystagmus in the rabbit. Trends Neurosci 11:277–280
Donkelaar HJ ten, Boer-van Huizen R de, Schouten FTM, Eggen SIH (1981) Cells of origin of descending pathways to the spinal cord in the clawed toad (Xenopus laevis). Neuroscience 6:2297–2312
Ewert JP (1971) Single unit response of the toad's (Bufo americanus) caudal thalamus to visual objects. Z Vergl Physiol 74:81–102
Ewert JP, Hock FJ, Wietersheim A von (1974) Thalamus, Praetectum, Tectum: Retinale Topographie and physiologische Interaktion bei der Kröte Bufo bufo (L.). J Comp Physiol 92:343–356
Finkenstädt T (1980) Disinhibition of prey-catching in the salamander following thalamic-pretectal lesions. Naturwissenschaften 67:471
Finkenstädt T, Ebbesson SOE, Ewert JP (1983) Projections to the midbrain tectum in Salamandra salamandra L. Cell Tissue Res 234:39–55
Fite KV, Scalia F (1976) Central visual pathways in the frog. In: KV Fite (ed) The amphibian visual system. Academic Press, New York, pp 87–118
Fite KV, Reiner A, Hunt SP (1979) Optokinetic nystagmus and the accessory optic system of pigeon and turtle. Brain Behav Evol 16:192–202
Fritzsch B (1980) Retinal projections in European Salamandridae. Cell Tissue Res 213:325–341
Gioanni H, Rey J, Villalobos J, Richard D, Dalbera A (1983) Optokinetic nystagmus in the pigeon (Columba livid) II. Role of the pretectal nucleus of the accessory optic system (AOS). Exp Brain Res 50:237–247
Giolli RA, Blanks RHI, Torigoe Y (1984) Pretectal and brain stem projections of the medial terminal nucleus of the accessory optic system of the rabbit and rat as studied by anterograde and retrograde neuronal tracing methods. J Comp Neurol 227:228–251
Hanker JS, Yates PE, Metz CB, Rustioni A (1977) A new specific, sensitive and non-carcinogenic reagent for the demonstration of horseradish peroxidase. Histochem J 9:789–792
Herrick CJ (1948) The brain of the tiger salamander Ambystoma tigrinum. The University of Chicago Press, Chicago
Hoffmann KP, Schoppmann A (1981) A quantitative analysis of the direction-specific response of neurons in the cat's nucleus of the optic tract. Exp Brain Res 42:146–157
Ingle DJ (1980) Some effects of pretectum lesions on the frog's detection of stationary objects. Behav Brain Res 1:139–163
Jakway JS, Riss W (1972) Retinal projections in the tiger salamander Ambystoma tigrinum. Brain Behav Evol 5:401–442
Katte O, Hoffmann KP (1980) Direction specific neurons in the pretectum of the frog (Rana esculenta). J Comp Physiol 140:53–57
Lázár G (1969) Efferent pathways of the optic tectum in the frog. Acta Biol Acad Sci Hungaria 20:171–183
Lázár G (1973) Role of the accessory optic system in the optokinetic nystagmus of the frog. Brain Behav Evol 5:443–460
Lázár G (1983) Transection of the basal optic root in the frog abolishes vertical optokinetic head-nystagmus. Neurosci Lett 43:7–11
Lázár G, Alkonyi B, Toth B (1983) Re-investigation of the role of the accessory optic system and pretectum in the horizontal optokinetic head nystagmus of the frog. Lesion experiments. Acta Biol Hung 34:385–393
Manteuffel G (1982) The accessory optic system in the newt, Triturus cristatus: Unitary response properties from the basal optic neuropil. Brain Behav Evol 21:175–184
Manteuffel G (1984) Electrophysiology and anatomy of direction specific pretectal units in Salamandra salamandra. Exp Brain Res 54:415–425
Manteuffel G (in press) Monocular and binocular optic inputs to salamander pretectal neurons: intracellular recording and HRP-labelling study. Brain Behav Evol
Manteuffel G, Petersen J, Himstedt W (1983) Optic nystagmus and nystagmogen centers in the European fire salamander (Salamandra salamandra). Zool Jb Physiol 87:113–125
Mesulam M-M, Hegarty E, Barbas H, Carson KA, Gower EC, Knapp AG, Moss MB, Mufson EJ (1980) Additional factors influencing sensitivity in the tetramethyl benzidine method for horseradish peroxidase neurohistochemistry. J Histochem Cytochem 28:1255–1259
Montgomery N, Fite KV, Bengston L (1981) The accessory optic system of Rana pipiens: Neuroanatomical connections and intrinsic organization. J Comp Neurol 203:595–612
Montgomery N, Fite KV, Taylor M, Bengston L (1982) Neural correlates of optokinetic nystagmus in the mesencephalon of Rana pipiens: A functional analysis. Brain Behav Evol 21:137–150
Montgomery N, Fite KV, Grigonis AM (1985) The pretectal nucleus (lentiformis mesencephali) of Rana pipiens. J Comp Neurol 234:264–275
Neary TJ, Northcutt RG (1983) Nuclear organization of the bullfrog diencephalon. J Comp Neurol 213:262–278
Nieuwenhuys R, Opdam P (1976) Brain stem. Structure of the brain stem. In: R. Llinas, W. Precht (eds) Frog neurobiology, pp 811–855
Opdam P, Nieuwenhuys R (1976) Topological analysis of the brain stem of the axolotl Ambystoma mexicanum. J Comp Neurol 165:285–306
Rettig G, Roth G (1982) Afferent visual projections in three species of lungless salamanders (Family Plethodontidae). Neurosci Lett 31:221–224
Scalia F, Gregory K (1970) Retinofugal projections in the frog: Location of the postsynaptic neurons. Brain Behav Evol 3:16–29
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Naujoks-Manteuffel, C., Manteuffel, G. Internuclear connections between the pretectum and the accessory optic system in Salamandra salamandra . Cell Tissue Res. 243, 595–602 (1986). https://doi.org/10.1007/BF00218067
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DOI: https://doi.org/10.1007/BF00218067