Skip to main content
SpringerLink
Log in

Effects of brain lesions on gonadotrop ultrastructure and serum gonadotropin levels in goldfish

  • Published:
Cell and Tissue Research Aims and scope Submit manuscript

Summary

Brain lesions that destroyed the anterior preoptic region or the pituitary stalk in sexually mature (= completed ovarian recrudescence) goldfish caused a significant increase in serum gonadotropin levels for at least 11 days postoperatively. These results confirmed previous findings indicating the presence of a gonadotropin release-inhibitory factor. Electron-microscopic investigation revealed that the gonadotrops were depleted of the small secretory granules, had marked dilations of the cisternae of the endoplasmic reticulum and extensive development of the Golgi apparatus. This indicated both secretion and synthesis, and correlated with the prolonged increase in serum gonadotropin resulting from the lesions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Cook AF, Peter RE (1980) Plasma clearance of gonadotropin in goldfish, Carassius auratus, during the annual reproductive cycle. Gen Comp Endocrinol 42:76–90

    Google Scholar 

  • Crim LW, Peter RE, Billard R (1976) Stimulation of gonadotropin secretion by intraventricular injection of hypothalamic extracts in the goldfish, Carassius auratus. Gen Comp Endocrinol 30:77–82

    Google Scholar 

  • Hontela A, Peter RE (1978) Daily cycles in serum gonadotropin levels in the goldfish: effects of photoperiod, temperature and sexual condition. Can J Zool 56:2430–2442

    Google Scholar 

  • Idler DR, Ng TB (1979) Studies on two types of gonadotropins from both salmon and carp pituitaries. Gen Comp Endocrinol 38:421–440

    Google Scholar 

  • Kaul S, Vollrath L (1974) The goldfish pituitary I. Cytology. Cell Tissue Res 154:211–230

    Google Scholar 

  • Lam TJ, Pandey S, Nagahama Y, Hoar WS (1976) Effect of synthetic luteinizing hormone-releasing hormone (LH-RH) on ovulation and pituitary cytology of the goldfish Carassius auratus. Can J Zool 54:816–824

    Google Scholar 

  • Leatherland JF (1972) Histophysiology and innervation of the pituitary gland of the goldfish, Carassiusauratus L.: a light and electron microscope investigation. Can J Zool 50:835–844

    Google Scholar 

  • Nagahama Y (1973) Histo-physiological studies on the pituitary gland of some teleost fishes, with special reference to the classification of hormone-producing cells in the adenohypophysis. Mem Fac Fish, Hokkaido Univ 21:1–63

    Google Scholar 

  • Nagahama Y, Yamamoto K (1969) Basophils in the adenohypophysis of the goldfish (Carassius auratus). Gunma Symp Endocrinol 6:39–55

    Google Scholar 

  • Peter RE (1980) Serum gonadotropin levels in mature male goldfish in response to luteinizing hormonereleasing hormone (LH-RH) anddes-Gly10-[D-Ala6]-LH-RH ethylamide. Can J Zool 58:1100–1104

    Google Scholar 

  • Peter RE (1982) Neuroendocrine control of reproduction in teleosts. Can J Fish Aquat Sci 39:48–55

    Google Scholar 

  • Peter RE, Gill VE (1975) A stereotaxic atlas and technique for forebrain nuclei of the goldfish, Carassius auratus. J Comp Neurol 159:69–102

    Google Scholar 

  • Peter RE, Nagahama Y (1976) A light and electron microscopic study of the structure of the nucleus preopticus and nucleus lateral tuberis of the goldfish, Carassius auratus. Can J Zool 54:1423–1437

    Google Scholar 

  • Peter RE, Paulencu CR (1980) Involvement of the preoptic region in gonadotropin release-inhibition in goldfish, Carassius auratus. Neuroendocrinology 31:133–141

    Google Scholar 

  • Peter RE, Crim LW, Goos HJTh, Crim JW (1978) Lesioning studies on the gravid female goldfish: neuroendocrine regulation of ovulation. Gen Comp Endocrinol 35:391–401

    Google Scholar 

  • Peter RE, Kah O, Paulencu CR, Cook H, Kyle AL (1980) Brain lesions and short-term endocrine effects of monosodium L-glutamate in goldfish, Carassius auratus. Cell Tissue Res 212:429–442

    Google Scholar 

  • Stacey NE, Cook AF, Peter RE (1979a) Ovulatory surge of gonadotropin in the goldfish, Carassius auratus. Gen Comp Endocrinol 37:246–249

    Google Scholar 

  • Stacey NE, Cook AF, Peter RE (1979b) Spontaneous and gonadotropin-induced ovulation in the goldfish, Carassius auratus L.: Effects of external factors. J Fish Biol 15:349–361

    Google Scholar 

  • Yamazaki F (1965) Endocrinological studies on the reproduction of the goldfish, Carassius auratus, with special reference to the function of the pituitary gland. Mem Fac Fish, Hokkaido Univ 13:1–64

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Zoology, University of British Columbia, Vancouver, B.C., Canada

    Y. Nagahama

  2. Department of Zoology, University of Alberta, Edmonton, Alberta, Canada

    R. E. Peter

Authors
  1. Y. Nagahama
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. E. Peter
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported by grants from Natural Sciences and Engineering Research Council of Canada to W.S. Hoar and R.E. Peter

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nagahama, Y., Peter, R.E. Effects of brain lesions on gonadotrop ultrastructure and serum gonadotropin levels in goldfish. Cell Tissue Res. 225, 259–265 (1982). https://doi.org/10.1007/BF00214680

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00214680

Key words

Search

Navigation