Abstract
We report four DNA variants in the gene coding for the cell adhesion molecule E-cadherin. The polymorphisms affect codons 115, 133, 582 and the 3′-noncoding region.
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Becker KF, Atkinson MJ, Reich U, Becker I, Nekarda H, Siewert JR, Höfler H (1994) E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res 54:3845–3852
Carter BS, Ewing CM, Ward WS, Treiger BF, Aalders TW, Schalken JA, Epstein JI, Isaacs WB (1990) Allelic loss of chromosomes 16q and lOq in human prostate cancer. Proc Natl Acad Sci USA 87:8751–8755
Natt E, Magenis RE, Zimmer J, Mansouri A, Scherer G (1989) Regional assignment of the human loci for uvomorulin (UVO) and chymotrypsinogen B (CTRB) with the help of two overlapping deletions of the long arm of chromosome 16. Cytogenet Cell Genet 30:145–148
Sato T, Tanigami A, Yamakawa K, Akiyama F, Kasumi F, Sakamoto G, Nakamura Y (1990) Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res 50:7184–7189
Takeichi M (1991) Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451–1455
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Becker, KF., Reich, U., Schott, C. et al. Single nucleotide polymorphisms in the human E-cadherin gene. Hum Genet 96, 739–740 (1995). https://doi.org/10.1007/BF00210311
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DOI: https://doi.org/10.1007/BF00210311