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A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by the polymerase chain reaction

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Abstract

A polymorphism that results in the loss of a CfoI site in the human cytochrome P450 CYP2D6 gene is described. This polymorphism does not appear to cause impaired enzyme activity.

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References

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Authors and Affiliations

  1. Pharmacogenetics Research Unit, Department of Pharmacological Sciences, University of Newcastle upon Tyne, Medical School, Framlington Place, NE2 4HH, Newcastle upon Tyne, UK

    Martin Armstrong, Jeffrey R. Idle & Ann K. Daly

Authors
  1. Martin Armstrong
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  2. Jeffrey R. Idle
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  3. Ann K. Daly
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Armstrong, M., Idle, J.R. & Daly, A.K. A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by the polymerase chain reaction. Hum Genet 91, 616–617 (1993). https://doi.org/10.1007/BF00205091

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  • DOI: https://doi.org/10.1007/BF00205091

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