Abstract
Skeletal manifestations of chloroma were reviewed in five patients. In four cases, a chloroma was the initial manifestation of a systemic disease. In the fifth, an elderly patient developed a bone lesion during a blastic crisis while under treatment for chronic myelogenous leukemia. Two patients presented with lytic lesions of the ribs, two with lytic lesions of the femur, and one with a predominantly sclerotic lesion of the scapula. The laboratory findings in two patients were within normal limits. All lesions were confirmed by bone biopsy.
Similar content being viewed by others
References
Austin JHM (1969) Chloroma: report of a patient with unusual rib lesions. Radiology 93:671
Barnett MJ, Zussman WV (1986) Granulocytic sarcoma of the brain: a case report and review of the literature. Radiology 160:223
Breatnach E, Stanley RJ, Carpenter JT Jr (1985) Intrarenal cloroma causing obstructive nephropathy: CT characteristics. Case report. J Comput Assist Tomogr 9(4):822
Brooks HW, Evans AE, Glass RM, Pang EM (1974) Chloromas of the head and neck in childhood. The initial manifestation of myeloid leukemia in three patients. Arch Otolaryngol 100:306
Burns A (1811) Observations on the surgical anatomy of the head and neck. Thomas Bryce, Edinburgh, p 364
Cavdar AO, Arcasoy A, Babacan E, Gozdasoglu S, Topuz U, Fraumeni JF (1978) Ocular granulocytic sarcoma (chloroma) with acute myelomonocytic leukemia in Turkish children. Cancer 41:1606
Dunnick NR, Heaston DK (1982) Computed tomography of extracranial chloroma. J Comput Assist Tomogr 6(1):81
Kandel EV (1937) Chloroma: review of literature from 1926 to 1936 and report of three cases. Arch Int Med 59:691
King A (1853) A case of chloroma. Monthly J Med 17:97
Libson E, Bloom RA, Galun E, Pollack A (1986) Granulocytic sarcoma (chloroma) of bone: the CT appearance. Comput Radiol 10(4):175
Meis JM, Butler JJ, Osborne BM, Manning JT (1986) Granulocytic sarcoma in nonleukemic patients. Cancer 58:2697
Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE, Bennett JM (1981) Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer 48(6):1426
Pomeranz SJ, Hawkins HH, Towbin R, Lisberg WN, Clark RA (1985) Granulocytic sarcoma (chloroma): CT manifestations. Radiology 155:167
Rappaport H (1966) Tumors of the hematopoietic system. Armed Forces Institute of Pathology, Washington DC, p 241 (Atlas of Tumor Pathology, Section III, Fascicle 8)
Schabel SI, Tyminski L, Holland D, Rittenberg GM (1980) The skeletal manifestations of chronic myelogenous leukemia. Skeletal Radiol 5:145
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hermann, G., Feldman, F., Abdelwahab, I.F. et al. Skeletal manifestations of granulocytic sarcoma (chloroma). Skeletal Radiol. 20, 509–512 (1991). https://doi.org/10.1007/BF00194248
Issue Date:
DOI: https://doi.org/10.1007/BF00194248