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Primary orbital malignant lymphoma: a clinicopathology study of 17 cases

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Abstract

We investigated the clinicopathologic characteristics of 17 patients (13 men and 4 women) with primary orbital malignant lymphoma using the Working Formulation. Most of the cases belonged to the low-grade malignancy group, and more women than men were in the histologically high-grade malignancy group. The phenotype of the tumor cells was investigated immunohistochemically. All cases showed the monoclonal feature of a B-cell lineage. All patients received chemotherapy with or without radiotherapy. Of 16 subjects, 15 achieved a complete remission; none of these patients has had a recurrence since the completion of the initial therapy (range of follow-up from 16 months to 10 years). One patient died.

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Nikaido, H., Mishima, H.K., Kiuchi, Y. et al. Primary orbital malignant lymphoma: a clinicopathology study of 17 cases. Graefe's Arch Clin Exp Ophthalmol 229, 206–209 (1991). https://doi.org/10.1007/BF00167868

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