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Rejected human corneal grafts II. Light and electron microscopic study

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Abstract

Six rejected human corneal grafts out of a group of 40 ‘bad-risk corneas’ were systematically studied by light and electron microscopy. Remarkable fine structural similarities in this sample of corneas were observed. Granulocytes, lymphocytes and plasma cells are common in all rejected grafts. Furthermore the epithelial and endothelial linings and the stroma reveal characteristic alterations. The observations indicate an immunological reaction of the recipient to the donor corneas.

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Author notes

  1. J. J. L. Van Der Want & G. Vrensen

    Present address: Dept. Morphology, The Netherlands Ophthalmic Research Institute, P:O. Box 6411, 1005, EK Amsterdam, The Netherlands

  2. C. C. Kok-Van Alphen & H. J. M. Völker-Dieben

    Present address: Eye Clinic University Hospital, Rijnsburgerweg 10, 2333, AA Leiden, The Netherlands

Authors and Affiliations

  1. Amsterdam/Leiden, The Netherlands

    J. J. L. Van Der Want, C. C. Kok-Van Alphen, G. Vrensen & H. J. M. Völker-Dieben

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  1. J. J. L. Van Der Want
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  2. C. C. Kok-Van Alphen
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  3. G. Vrensen
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  4. H. J. M. Völker-Dieben
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Van Der Want, J.J.L., Kok-Van Alphen, C.C., Vrensen, G. et al. Rejected human corneal grafts II. Light and electron microscopic study. Doc Ophthalmol 50, 343–356 (1981). https://doi.org/10.1007/BF00158019

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