Summary
The joint effects of the initial concentration of N and P on the production of citric acid by 11 strains of Aspergillus niger on an effluent are studied by means of orthogonal full-factorial 22 designs. The results allow the definition of a series of empirical equations describing well differentiated types of behaviour. This demonstrates the usefulness of the procedure followed in order to establish selection criteria for the more suitable strains, to determine the tendencies that permit approaching optimum production and evaluate the viability of different culture options characterized by discontinuous feeding of one or another nutrient.
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References
Akhnazarova, S. & V. Kafarov (1982): In Experiment Optimization in Chemistry and Chemical Engineering. MIR Publ. (Moscow).
Bernfeld, P. (1951): Adv. Enzymol., 12: 379–427.
Box, G.E.P., W.G. Hunter & J.S. Hunter (1989): In Estadística para investigations. Ed. Reverié Reverié (Barcelona).
Chapman, G.W. & J. Horvat (1989): J. Agric. Food Chem., 37: 947–50.
Dawson, M.W., I.S. Maddox & J.D. Brooks (1989): Biotechnol. Bioeng., 33: 1500–04.
Forouhi, E. & D.J. Gunn (1983): Biotechnol. Bioeng., 25: 1905–11.
Havilah, E.J., D.M. Wallis, R. Morris & J.A. Woolnough (1977): Lab. Practice, July: 545-47.
Kapoor, K.K., K. Chaudhary & P. Tauro (1982). In Prescott & Dunn's Industrial Microbiology. Ed. by G. Reed. Macmlllan (Connecticut).
Kristiansen, B. & C.G. Sinclair (1978): Biotechnol. Bioeng., 20: 1711–22.
Kubicek, C.P. & M. Rhor (1986): CRC Critical Rev. Biotechnol., 3: 331–73.
Marier, J.R. & M. Boulet (1958): J. Diary Sci., 41, 1683–1692.
Murado, M.A., MaP. Gonzalez, L. Pastrana, MaI.G. Siso, J. Miron & MaI. Montemayor (1993): Bioresource Technol., 44: 155–63.
Pastrana, L. (1991): Thesis. Fac. Farmacia. Univ. Santiago de Compostela (Spain).
Strickland, J.D.H. & T.R. Parsons (1968): J. Fish. Res. Board Canada, 167, 173–74.
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Pintado, J., Murado, M.A., Gonzalez, M. et al. Joint effect of nitrogen and phosphorus concentrations on citric acid production by different strains of Aspergillus niger grown on an effluent. Biotechnol Lett 15, 1157–1162 (1993). https://doi.org/10.1007/BF00131208
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DOI: https://doi.org/10.1007/BF00131208