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Overproduction of alanine by Arthrobacter strains with glucose-nonrepressible L-alanine dehydrogenase

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Summary

Two Arthrobacter strains were identified as having high alanine productivity and L-alanine dehydrogenase (ADH) activity upon growth on glucose. They excreted large amounts of DL-alanine (37 and 81 g/1), but Bacillus sphaericus with glucose-repressible ADH did not at all. These results suggest that the glucose-nonrepressible ADH might be involved in alanine overproduction in the Arthrobacter strains.

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  1. Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Asahi-machi, Machida-shi, 194, Tokyo, Japan

    Shin-ichi Hashimoto & Ryoichi Katsumata

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  1. Shin-ichi Hashimoto
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  2. Ryoichi Katsumata
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Hashimoto, Si., Katsumata, R. Overproduction of alanine by Arthrobacter strains with glucose-nonrepressible L-alanine dehydrogenase. Biotechnol Lett 15, 1117–1122 (1993). https://doi.org/10.1007/BF00131200

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