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Hydrophobicity of the cell surface and drug susceptibility of Escherichia coli cultivated at high pressures up to 30 MPa

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Summary

Escherichia coli was cultivated under hydrostatic pressures up to 30 MPa (300 bar) and then partitioned between an aqueous phase (physiological saline) and oil phase (n-hexadecane). The partition coefficients were used as measures of hydrophobicity of the surface of the cells and correlated with the susceptibility to an antimicrobial agent (dodecylpyridinium iodide). This agent is lethal to the cells and the effect of pressure on its concentration for a lethal effect on E. coli was determined. A good correlation was found between the hydrophobicity of the cells and their death rate on treatment with this reagent.

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References

  • Tamura, K., Shimizu, T., and Kourai, H. (1992). FEMS Microbiol. Lett. 99, 321–324.

    Google Scholar 

  • Kourai, H., Takechi, H., Muramatsu, K., and Shibasaki, I. (1989). J. Antibact. Antifung. Agents 17, 119–128.

    Google Scholar 

  • Marshall, K. C., Stout, R., and Mitchell, R. (1971). J. Gen. Microbiol. 68, 337–348.

    Google Scholar 

  • Marshall, K. C., Stout, R., and Mitchell, R., (1971). J. Microbiol. 17, 1413–1416.

    Google Scholar 

  • Magnusson, K. E. and Johansoon, G. (1977). FEMS Microbiol. Lett. 2, 225–258.

    Google Scholar 

  • Smyth, C. J., Jonsson, P., Olsson, E., Söderlind, O., Rosengren, J., Hjertén, S., and Wadström, T. (1978). Infect. Immun. 22, 462–472.

    Google Scholar 

  • Lindahl, M., Faris, A., Wadström, T., and Hjertén, S. (1981). Biochim. Biophys. Acta 677, 471–476.

    Google Scholar 

  • Moriyoshi, T. and Tamura, K. (1970). Rev. Phys. Chem. Jpn. 40,48–58.

    Google Scholar 

  • Kourai, H. (1991). Rep. Chem. Mat. R & D Found 6, 55–61 (Japanese).

    Google Scholar 

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Authors and Affiliations

  1. Department of Chemical Science and Technology, Faculty of Engineering, The University of Tokushima, Minamijosanjima-cho, 770, Tokushima, Japan

    Katsuhiro Tamura, Yoshihisa Muramoto & Hiroki Kourai

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  1. Katsuhiro Tamura
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  2. Yoshihisa Muramoto
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  3. Hiroki Kourai
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Tamura, K., Muramoto, Y. & Kourai, H. Hydrophobicity of the cell surface and drug susceptibility of Escherichia coli cultivated at high pressures up to 30 MPa. Biotechnol Lett 15, 1189–1194 (1993). https://doi.org/10.1007/BF00130295

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  • DOI: https://doi.org/10.1007/BF00130295

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