Skip to main content
Log in

First enantioselective hydrolysis of n-alkyl sec-alkyl carbonates by porcine pancreatic lipase

  • Published:
Biotechnology Letters Aims and scope Submit manuscript

Summary

n-Alkyl sec-alkyl carbonates were enantioselectively hydrolyzed by porcine pancreatic lipase to give optically active (R)-sec-alkanols. (R)-1-Phenylethanol with an optical purity of >99%ee was obtained by the resolving method.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Boland, W., Fröβl, C., and Lorenz, M. (1991). Synthesis 1049–1072.

  • Naoshima, Y., Munakata, Y., Yoshida, S., and Funai, A. (1991). J. Chem. Soc., Perkin Trans 1 549–553.

    Google Scholar 

  • Abramowicz, D. A. and Keese, C. R. (1989). Biotechnol. Bioeng. 33, 149–156.

    Google Scholar 

  • Andreoni, V., Baggi, G., Bernasconi, S., Foglieni, C., and Pelizzoni, F. (1990). Appl. Microbiol. Biotechnol. 33, 633–636.

    Google Scholar 

  • Kawashima, M. and Hasegawa, T. (1992). Biotechnol. Lett. 14, 1135–1136.

    Google Scholar 

  • Chen, C. -S., Fujimoto, Y., Girdaukas, G., and Sih, C. J. (1982). J. Am. Chem. Soc. 104, 7294–7299.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kawashima, M., Hasegawa, T. First enantioselective hydrolysis of n-alkyl sec-alkyl carbonates by porcine pancreatic lipase. Biotechnol Lett 15, 465–468 (1993). https://doi.org/10.1007/BF00129319

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00129319

Keywords

Navigation