Skip to main content
SpringerLink
Log in

„Ich habe Parkinson, soll ich Juckbohnenextrakt einnehmen?“

  • Fortbildung
  • Published:
DNP - Der Neurologe und Psychiater Aims and scope

Als Neurologe hört man früher oder später die Frage eines Parkinson-Patienten, ob es sinnvoll wäre, die Erkrankung mit Juckbohnen zu behandeln. Wer gezielt nachfragt, wird überrascht sein, wie viele Patienten bereits neben der verschriebenen Medikation Kapseln mit Juckbohnenextrakt einnehmen. Etwas Hintergrundwissen könnte daher für die Beratung von Patienten hilfreich sein.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Brauckmann BM, Latté KP. L-Dopa aus den Bohnen Vicia faba und Mucuna pruriens als Wirkstoff gegen Morbus Parkinson. Schweiz Z Ganzheitsmed 2010; 22: 1–9

    Article  Google Scholar 

  2. https://en.wikipedia.org/wiki/Ayurveda

  3. Manyam BV. Paralysis agitans and levodopa in „Ayurveda“: ancient Indian medical treatise. Mov Disord 1990; 5(1): 47–8

    Article  CAS  PubMed  Google Scholar 

  4. Ovallath S, Deepa P. The history of parkin- sonism: descriptions in ancient Indian medical literature. Mov Disord 2013; 28(5): 566–8

    Article  PubMed  Google Scholar 

  5. Shelley WB, Arthur RP. Mucunain, the active pruritogenic proteinase of cowhage. Science 1955; 122(3167): 469–70

    Article  CAS  PubMed  Google Scholar 

  6. Ramya KB, Thaakur S. Herbs containing L-Dopa: An update. Anc Sci Life 2007; 27(1): 50–5

    PubMed  PubMed Central  Google Scholar 

  7. Gish M, Mescher MC, De Moraes CM. Targeted predation of extrafloral nectaries by insects despite localized chemical defences. Proc Biol Sci 2015; 282(1816):20151835

    Article  PubMed  Google Scholar 

  8. Soares AR et al. The role of L-DOPA in plants. Plant Signal Behav 2014; 9(4): e28275

    Article  PubMed Central  Google Scholar 

  9. Sridhar KR, Bhat R. Agrobotanical, nutritional and bioactive potential of unconventional legume - Mucuna. Livestock Research for Rural Development 2007; 19: article 126. http://www.lrrd.org/lrrd19/9/srid19126.htm

  10. Infante ME et al. Outbreak of acute toxic psychosis attributed to Mucuna pruriens. Lancet 1990; 336(8723): 1129

    Article  CAS  PubMed  Google Scholar 

  11. Lieu CA et al. A water extract of Mucuna pruriens provides long-term amelioration of parkinsonism with reduced risk for dyskinesias. Parkinsonism Relat Disord 2010; 16(7):458–65

    Article  PubMed  PubMed Central  Google Scholar 

  12. Yadav SK et al. Comparison of the neuroprotective potential of Mucuna pruriens seed extract with estrogen in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mice model. Neurochem Int 2014; 65:1–13

    Article  CAS  PubMed  Google Scholar 

  13. http://www.zanduayurveda.com

  14. Lampariello LR et al. The Magic Velvet Bean of Mucuna pruriens. J Tradit Complement Med 2012; 2(4):331–9

    PubMed  PubMed Central  Google Scholar 

  15. http://mit-phytaminen-heilen.com/heilpflanzen/mucuna_pruriens.html

  16. http://mit-phytaminen-heilen.com/heilpflanzen/gokshura.html

  17. Lieu CA et al. The Antiparkinsonian and Antidyskinetic Mechanisms of Mucuna pruriens in the MPTP-Treated Nonhuman Primate. Evid Based Complement Alternat Med, 2012; 2012: 840247

    Article  PubMed  PubMed Central  Google Scholar 

  18. Lieu CA et al. Dyskinesias do not develop after chronic intermittent levodopa therapy in clinically hemiparkinsonian rhesus monkeys. Parkinsonism Relat Disord 2011; 17(1): 34–9

    Article  PubMed  Google Scholar 

  19. Hussian G, Manyam BV. Mucuna pruriens proves more effective than L-Dopa in Parkinson’s disease animal model. Phytotherapy Res 1997; 11(6):419–23

    Article  Google Scholar 

  20. Kasture S et al. Assessment of symptomatic and neuroprotective efficacy of Mucuna pruriens seed extract in rodent model of Parkinson’s disease. Neurotox Res 2009; 15(2):111–22

    Article  PubMed  Google Scholar 

  21. Poddighe S et al. Mucuna pruriens (Velvet bean) rescues motor, olfactory, mitochondrial and synaptic impairment in PINK1B9 Drosophila melanogaster genetic model of Parkinson’s disease. PLoS One, 2014; 9(10):e110802

    Article  PubMed  PubMed Central  Google Scholar 

  22. Misra L, Wagner H. Extraction of bioactive principles from Mucuna pruriens seeds. Indian J of Biochemistry & Biophysics 2007; 44:56–60

    CAS  Google Scholar 

  23. Vaidya AB et al. Treatment of Parkinson’s disease with the cowhage plant-Mucuna pruriens Bak. Neurol India 1978; 26(4):171–6

    CAS  PubMed  Google Scholar 

  24. Manyam BV. An Alternative Medicine Treatment for Parkinson’s Disease: Results of a Multicenter Clinical Trial. J Altern Complement Med 1995; 1(3):249–55

    Article  Google Scholar 

  25. Mahajani SS et al. Bioavailability of L-DOPA from HP-200-a Formulation of Seed Powder of Mucuna pruriens. Phytother Res 1996; 10:254–6

    Article  CAS  Google Scholar 

  26. Contin M et al. Mucuna pruriens in Parkinson Disease: A Kinetic-Dynamic Comparison With Levodopa Standard Formulations. Clin Neuropharmacol 2015; 38(5):201–3

    Article  CAS  PubMed  Google Scholar 

  27. Katzenschlager R et al. Mucuna pruriens in Parkinson’s disease: a double blind clinical and pharmacological study. J Neurol Neurosurg Psychiatry 2004; 75(12):1672–7

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Neurologische Klinik, Universitätsklinikum Freiburg, Breisacher Str. 64, 79106, Freiburg, Deutschland

    Michel Rijntjes

Authors
  1. Michel Rijntjes
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Michel Rijntjes.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rijntjes, M. „Ich habe Parkinson, soll ich Juckbohnenextrakt einnehmen?“. DNP 17, 40–42 (2016). https://doi.org/10.1007/s15202-016-1323-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s15202-016-1323-x

Search

Navigation