Abstract
Over 70,000 US young adults are diagnosed with cancer annually, disrupting important life transitions and goal pursuits. Hope is a positive psychology construct associated with better quality of life (QOL) that focuses on goal-oriented thinking. We developed and tested Achieving Wellness After Kancer in Early life (AWAKE), a scalable 8-week app-based program consisting of educational videos, mood/activity tracking, and telephone-based coaching to promote hope and QOL in young adult cancer survivors (YACS, 18–40 years old). A two-arm RCT was used to examine the feasibility, acceptability, and potential efficacy of AWAKE (n = 38) versus attention control (AC; n = 18) among YACS within 2 years of completing treatment and recruited from two NCI-designated cancer centers. Outcomes including hope (Trait Hope Scale), QOL (36-Item Short Form Health Survey; Functional Assessment of Cancer Therapy-General), depressive symptoms (Patient Health Questionnaire-9), and substance use were assessed at baseline, 8 weeks, and 6 months. Participants were an average of 32.55 (SD = 5.45) years old; 75.0% were female, and 80.4% White. The most common cancers were breast cancer (28.6%), melanoma (16.1%), and leukemia/lymphoma (12.5%). High retention, engagement, and satisfaction rates were documented in both conditions; AWAKE versus AC participants rated video content as more relevant (p = 0.007) and reported greater likelihood of talking positively about the program (p = 0.005). Many efficacy change scores showed positive trends in AWAKE versus AC. Reorienting to one’s goal pursuits after cancer diagnosis and treatment is critical and may be supported through hope-based interventions. Findings suggest that the AWAKE warrants subsequent research testing its efficacy, effectiveness, and scalability.
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Funding
This research was supported by Emory University’s Winship Cancer Institute (P30 CA138292; Winship Invests Pilot Program; PI: Berg). This project was supported by services from the University of Kentucky Markey Cancer Center Behavioral and Community-Based Research and Cancer Research Informatics Shared Resource Facilities (P30 CA177558).
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the Institutional Review Boards at Emory University (IRB00086979) and the University of Kentucky (16-0751-P2H) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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Berg, C.J., Vanderpool, R.C., Getachew, B. et al. A Hope-Based Intervention to Address Disrupted Goal Pursuits and Quality of Life Among Young Adult Cancer Survivors. J Canc Educ 35, 1158–1169 (2020). https://doi.org/10.1007/s13187-019-01574-7
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DOI: https://doi.org/10.1007/s13187-019-01574-7